Efficient 3D conformer generation of cyclic peptides formed by a disulfide bond
Abstract Cyclic peptides formed by disulfide bonds have been one large group of common drug candidates in drug development. Structural information of a peptide is essential to understand its interaction with its target. However, due to the high flexibility of peptides, it is difficult to sample the...
| Những tác giả chính: | , , , , |
|---|---|
| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
BMC
2022-05-01
|
| Loạt: | Journal of Cheminformatics |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://doi.org/10.1186/s13321-022-00605-8 |