EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT
The case of clinical observation over twin brothers (boys E. and N) suffering juvenile idiopathic arthritis is presented in the article. Boys fell ill with a difference in 1 year and 5 months at the age of 1 year and 9 months and 3 years 2 months, respectively. The disease proceeded wavily with the...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2014-05-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/200 |
| _version_ | 1797700417112506368 |
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| author | V. A. Kel'tsev |
| author_facet | V. A. Kel'tsev |
| author_sort | V. A. Kel'tsev |
| collection | DOAJ |
| description | The case of clinical observation over twin brothers (boys E. and N) suffering juvenile idiopathic arthritis is presented in the article. Boys fell ill with a difference in 1 year and 5 months at the age of 1 year and 9 months and 3 years 2 months, respectively. The disease proceeded wavily with the periods of remissions and exacerbations. Resistant articulate syndrome developed in July and November, 2009, respectively. Both children received NSAID, methotrexate combination in a dose of 10 mg/m2/week and sulphasalazine in a dose of 20 mg/kg of body weight per day. To the boy E. it was also prescripted prednisolon in a dose of 10 mg per day. Duration of antirheumatic therapy made 7 and 3 months, respectively. The therapy with a blocker of T-lymphocytes costimulation, abatacept, was initiated for the twins due to the inefficiency of treatment by immunodepressants and prednisolon at the boy E. In 6 weeks of the treatment 50% improvement, in 24 weeks — 90% improvement by criteria of the American College of Rheumatologists (ACRpedi) were registered. The undesirable phenomena weren’t observed. |
| first_indexed | 2024-03-12T04:21:37Z |
| format | Article |
| id | doaj.art-01eedd4143b24bb8949f7e5d88cfa0a0 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T04:21:37Z |
| publishDate | 2014-05-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-01eedd4143b24bb8949f7e5d88cfa0a02023-09-03T10:33:02Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352014-05-0113310410910.15690/vsp.v13i3.1036200EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPTV. A. Kel'tsev0Самарский государственный медицинский университетThe case of clinical observation over twin brothers (boys E. and N) suffering juvenile idiopathic arthritis is presented in the article. Boys fell ill with a difference in 1 year and 5 months at the age of 1 year and 9 months and 3 years 2 months, respectively. The disease proceeded wavily with the periods of remissions and exacerbations. Resistant articulate syndrome developed in July and November, 2009, respectively. Both children received NSAID, methotrexate combination in a dose of 10 mg/m2/week and sulphasalazine in a dose of 20 mg/kg of body weight per day. To the boy E. it was also prescripted prednisolon in a dose of 10 mg per day. Duration of antirheumatic therapy made 7 and 3 months, respectively. The therapy with a blocker of T-lymphocytes costimulation, abatacept, was initiated for the twins due to the inefficiency of treatment by immunodepressants and prednisolon at the boy E. In 6 weeks of the treatment 50% improvement, in 24 weeks — 90% improvement by criteria of the American College of Rheumatologists (ACRpedi) were registered. The undesirable phenomena weren’t observed.https://vsp.spr-journal.ru/jour/article/view/200детиблизнецыювенильный идиопатический артритабатацептлечение |
| spellingShingle | V. A. Kel'tsev EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT Вопросы современной педиатрии дети близнецы ювенильный идиопатический артрит абатацепт лечение |
| title | EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT |
| title_full | EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT |
| title_fullStr | EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT |
| title_full_unstemmed | EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT |
| title_short | EXPERIENCE OF TREATMENT OF THE TWINS SICK WITH JUVENILE IDIOPATHIC ARTHRITIS BY ABATACEPT |
| title_sort | experience of treatment of the twins sick with juvenile idiopathic arthritis by abatacept |
| topic | дети близнецы ювенильный идиопатический артрит абатацепт лечение |
| url | https://vsp.spr-journal.ru/jour/article/view/200 |
| work_keys_str_mv | AT vakeltsev experienceoftreatmentofthetwinssickwithjuvenileidiopathicarthritisbyabatacept |