Excess of heme induces tissue factor-dependent activation of coagulation in mice
An excess of free heme is present in the blood during many types of hemolytic anemia. This has been linked to organ damage caused by heme-mediated oxidative stress and vascular inflammation. We investigated the mechanism of heme-induced coagulation activation in vivo. Heme caused coagulation activat...
| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Ferrata Storti Foundation
2015-03-01
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| coleção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/7301 |