Sprouty4 is epigenetically upregulated in human colorectal cancer

Sprouty4 is epigenetically upregulated in human colorectal cancer

Sprouty4 (SPRY4) has been frequently reported as a tumor suppressor and is therefore downregulated in various cancers. For the first time, we report that SPRY4 is epigenetically upregulated in colorectal cancer (CRC). In this study, we explored DNA methylation and hydroxymethylation levels of SPRY4...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Alexei J. Stuckel, Shuai Zeng, Zhen Lyu, Wei Zhang, Xu Zhang, Urszula Dougherty, Reba Mustafi, Tripti Khare, Qiong Zhang, Trupti Joshi, Marc Bissonnette, Sharad Khare
Format: Artikel
Sprache:English
Veröffentlicht: Taylor & Francis Group 2023-12-01
Schriftenreihe:Epigenetics
Schlagworte:
colorectal cancer
sprouty4
gene expression
dna methylation
dna hydroxymethylation
Online Zugang:http://dx.doi.org/10.1080/15592294.2022.2145068

Online

http://dx.doi.org/10.1080/15592294.2022.2145068

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