Sex differences in readmission rate after cardiac surgery

IntroductionThe impact of sex on hospital readmission rate after cardiac surgery is unclear. Therefore, we aimed to analyse sex-specific differences and underlying factors in 30-day readmission rate after cardiac surgery.MethodsWe conducted a single center study including all patients after major ca...

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Main Authors: Luca Koechlin, Jules Miazza, Brigitta Gahl, David Santer, Luise Vöhringer, Denis Berdajs, Friedrich S. Eckstein, Oliver Reuthebuch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1273785/full
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author Luca Koechlin
Jules Miazza
Brigitta Gahl
Brigitta Gahl
David Santer
David Santer
Luise Vöhringer
Denis Berdajs
Denis Berdajs
Friedrich S. Eckstein
Friedrich S. Eckstein
Oliver Reuthebuch
Oliver Reuthebuch
author_facet Luca Koechlin
Jules Miazza
Brigitta Gahl
Brigitta Gahl
David Santer
David Santer
Luise Vöhringer
Denis Berdajs
Denis Berdajs
Friedrich S. Eckstein
Friedrich S. Eckstein
Oliver Reuthebuch
Oliver Reuthebuch
author_sort Luca Koechlin
collection DOAJ
description IntroductionThe impact of sex on hospital readmission rate after cardiac surgery is unclear. Therefore, we aimed to analyse sex-specific differences and underlying factors in 30-day readmission rate after cardiac surgery.MethodsWe conducted a single center study including all patients after major cardiac surgery (excluding aortic dissection and left ventricular assist device implantation) from January 2012 to September 2020. Reasons for readmission were adjudicated according to all available medical records. We calculated incidence rate ratios (IRR) with 95% confidence intervals (CI) for female sex with re-admission crude and adjusted for plausible confounding factors using negative binomial regression.Results4,868 patients were included in the analysis. The median [Interquartile range] age was 68 [60 to 74] years and 24% (n = 1,149) of the patients were female. Female patients were significantly older (median [IQR] age 70 (63 to 76) vs. 67 (59 to 74), p < 0.001) and had lower body mass index and fewer cardiovascular risk factors compared to men. Isolated valve surgery was more frequent in female while coronary artery bypass grafting was more often in men. 30-day readmission was comparable between both sexes (7.0% [n = 81] in female vs. 8.7% [n = 322] in men; p = 0.078). Cardiac related readmissions and infections were the most common reasons for readmission in both groups. The overall incidence rate ratios of female sex with readmission (0.80, 95% CI 0.63 to 1.03, p = 0.078) remained robust after adjustment for EuroSCORE 2 (0.78, CI 0.61 to 1.0, p = 0.051).ConclusionReadmission rate and reasons for 30-day readmission after major cardiac surgery were similar between men and women.
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spelling doaj.art-01f8c21494cd4f5ba1538205f6902c952023-10-11T05:55:38ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-10-011010.3389/fcvm.2023.12737851273785Sex differences in readmission rate after cardiac surgeryLuca Koechlin0Jules Miazza1Brigitta Gahl2Brigitta Gahl3David Santer4David Santer5Luise Vöhringer6Denis Berdajs7Denis Berdajs8Friedrich S. Eckstein9Friedrich S. Eckstein10Oliver Reuthebuch11Oliver Reuthebuch12Department of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandSurgical Outcome Research Centre Basel, University Hospital Basel, University Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandMedical Faculty of the University of Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandMedical Faculty of the University of Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandMedical Faculty of the University of Basel, Basel, SwitzerlandDepartment of Cardiac Surgery, University Hospital Basel, Basel, SwitzerlandMedical Faculty of the University of Basel, Basel, SwitzerlandIntroductionThe impact of sex on hospital readmission rate after cardiac surgery is unclear. Therefore, we aimed to analyse sex-specific differences and underlying factors in 30-day readmission rate after cardiac surgery.MethodsWe conducted a single center study including all patients after major cardiac surgery (excluding aortic dissection and left ventricular assist device implantation) from January 2012 to September 2020. Reasons for readmission were adjudicated according to all available medical records. We calculated incidence rate ratios (IRR) with 95% confidence intervals (CI) for female sex with re-admission crude and adjusted for plausible confounding factors using negative binomial regression.Results4,868 patients were included in the analysis. The median [Interquartile range] age was 68 [60 to 74] years and 24% (n = 1,149) of the patients were female. Female patients were significantly older (median [IQR] age 70 (63 to 76) vs. 67 (59 to 74), p < 0.001) and had lower body mass index and fewer cardiovascular risk factors compared to men. Isolated valve surgery was more frequent in female while coronary artery bypass grafting was more often in men. 30-day readmission was comparable between both sexes (7.0% [n = 81] in female vs. 8.7% [n = 322] in men; p = 0.078). Cardiac related readmissions and infections were the most common reasons for readmission in both groups. The overall incidence rate ratios of female sex with readmission (0.80, 95% CI 0.63 to 1.03, p = 0.078) remained robust after adjustment for EuroSCORE 2 (0.78, CI 0.61 to 1.0, p = 0.051).ConclusionReadmission rate and reasons for 30-day readmission after major cardiac surgery were similar between men and women.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1273785/fullcardiac surgeryreadmissionhealth caresex differencesepidemiology
spellingShingle Luca Koechlin
Jules Miazza
Brigitta Gahl
Brigitta Gahl
David Santer
David Santer
Luise Vöhringer
Denis Berdajs
Denis Berdajs
Friedrich S. Eckstein
Friedrich S. Eckstein
Oliver Reuthebuch
Oliver Reuthebuch
Sex differences in readmission rate after cardiac surgery
Frontiers in Cardiovascular Medicine
cardiac surgery
readmission
health care
sex differences
epidemiology
title Sex differences in readmission rate after cardiac surgery
title_full Sex differences in readmission rate after cardiac surgery
title_fullStr Sex differences in readmission rate after cardiac surgery
title_full_unstemmed Sex differences in readmission rate after cardiac surgery
title_short Sex differences in readmission rate after cardiac surgery
title_sort sex differences in readmission rate after cardiac surgery
topic cardiac surgery
readmission
health care
sex differences
epidemiology
url https://www.frontiersin.org/articles/10.3389/fcvm.2023.1273785/full
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