Signaling pathways and intervention therapies in sepsis

Abstract Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host systemic inflammatory and immune response to infection. Over decades, advanced understanding of host–microorganism interaction has gradually unmasked the genuine nature of sepsis, guiding toward new definiti...

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Bibliographic Details
Main Authors: Yun-yu Zhang, Bo-tao Ning
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00816-9

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