Systemization for the management of acid-base balance in seriously ill patients

Introduction: Acid-base balance alterations can be of a primary nature. In most cases, they depend on the complication of a pre-existing disease. The frequency of these disorders is high, especially in patients hospitalized in critical care units. Its appearance carries significant prognostic implic...

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Main Authors: Pablo Joel Morejón Esperón, Jean Le’Clerc Nicolás, Anabel Hernandez Ruiz
Format: Article
Language:Spanish
Published: Centro Nacional de Información de Ciencias Médicas. Editorial de Ciencias Médicas (ECIMED) 2022-01-01
Series:Revista Cubana de Anestesiología y Reanimación
Subjects:
Online Access:http://revanestesia.sld.cu/index.php/anestRean/article/view/720
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author Pablo Joel Morejón Esperón
Jean Le’Clerc Nicolás
Anabel Hernandez Ruiz
author_facet Pablo Joel Morejón Esperón
Jean Le’Clerc Nicolás
Anabel Hernandez Ruiz
author_sort Pablo Joel Morejón Esperón
collection DOAJ
description Introduction: Acid-base balance alterations can be of a primary nature. In most cases, they depend on the complication of a pre-existing disease. The frequency of these disorders is high, especially in patients hospitalized in critical care units. Its appearance carries significant prognostic implications. Objective: To systematize the current state of acid-base balance management. Method: A bibliographic review was carried out, for which the tools of the scientific method were used. All the available bibliography, published in the last five years, was examined; thus, a critical synthesis was prepared, according to the criteria and competences of the authors regarding the subject. Results: The importance of the clinical evaluation is exposed, which, together with PCO2 levels as well as excess or deficit of bases in an arterial blood gas, allow to identify the existing acid-base disorder. Likewise, it is highlighted that CO2 has a key function in ventilation control, together with the modifications it produces on cerebral blood flow, pH and adrenergic tone. Another important aspect was the recent clinical practice of “permissive hypercapnia” to reduce tissue metabolism and thus improve surfactant function and prevent protein nitration. Conclusions: The management of acid-base imbalances should be mastered by all professionals associated to medical care, since any delay in its diagnosis can worsen the evolution and prognosis of seriously ill patients.   Keywords: acid-base disorders; metabolic acidosis; metabolic alkalosis; respiratory acidosis; respiratory alkalosis.
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spelling doaj.art-02001aa3737640f2aeb7b1542c354e092022-12-22T04:03:36ZspaCentro Nacional de Información de Ciencias Médicas. Editorial de Ciencias Médicas (ECIMED)Revista Cubana de Anestesiología y Reanimación1726-67182022-01-01203613Systemization for the management of acid-base balance in seriously ill patientsPablo Joel Morejón Esperón0Jean Le’Clerc Nicolás1Anabel Hernandez Ruiz2Joaquín AlbarránJoaquín AlbarránHDCQ Joaquín Albarrán DomínguezIntroduction: Acid-base balance alterations can be of a primary nature. In most cases, they depend on the complication of a pre-existing disease. The frequency of these disorders is high, especially in patients hospitalized in critical care units. Its appearance carries significant prognostic implications. Objective: To systematize the current state of acid-base balance management. Method: A bibliographic review was carried out, for which the tools of the scientific method were used. All the available bibliography, published in the last five years, was examined; thus, a critical synthesis was prepared, according to the criteria and competences of the authors regarding the subject. Results: The importance of the clinical evaluation is exposed, which, together with PCO2 levels as well as excess or deficit of bases in an arterial blood gas, allow to identify the existing acid-base disorder. Likewise, it is highlighted that CO2 has a key function in ventilation control, together with the modifications it produces on cerebral blood flow, pH and adrenergic tone. Another important aspect was the recent clinical practice of “permissive hypercapnia” to reduce tissue metabolism and thus improve surfactant function and prevent protein nitration. Conclusions: The management of acid-base imbalances should be mastered by all professionals associated to medical care, since any delay in its diagnosis can worsen the evolution and prognosis of seriously ill patients.   Keywords: acid-base disorders; metabolic acidosis; metabolic alkalosis; respiratory acidosis; respiratory alkalosis.http://revanestesia.sld.cu/index.php/anestRean/article/view/720trastornos ácido base, acidosis metabólica, alcalosis metabólica, acidosis respiratoria, alcalosis respiratoria.
spellingShingle Pablo Joel Morejón Esperón
Jean Le’Clerc Nicolás
Anabel Hernandez Ruiz
Systemization for the management of acid-base balance in seriously ill patients
Revista Cubana de Anestesiología y Reanimación
trastornos ácido base, acidosis metabólica, alcalosis metabólica, acidosis respiratoria, alcalosis respiratoria.
title Systemization for the management of acid-base balance in seriously ill patients
title_full Systemization for the management of acid-base balance in seriously ill patients
title_fullStr Systemization for the management of acid-base balance in seriously ill patients
title_full_unstemmed Systemization for the management of acid-base balance in seriously ill patients
title_short Systemization for the management of acid-base balance in seriously ill patients
title_sort systemization for the management of acid base balance in seriously ill patients
topic trastornos ácido base, acidosis metabólica, alcalosis metabólica, acidosis respiratoria, alcalosis respiratoria.
url http://revanestesia.sld.cu/index.php/anestRean/article/view/720
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