Glycemic variability and mortality in oncologic intensive care units

ABSTRACT Objective: This study aimed to investigate the association between glycemic variability and mortality in patients admitted to oncologic intensive care units. Methods: A retrospective cohort study was conducted using a convenience sample of 30 medical records of patients over 18 years of a...

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Main Authors: Aretha Pereira de Oliveira, Mariana da Silva Castro, Dalmo Valério Machado de Lima
Format: Article
Language:English
Published: Associação Brasileira de Enfermagem 2023-10-01
Series:Revista Brasileira de Enfermagem
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71672023000800223&lng=en&tlng=en
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author Aretha Pereira de Oliveira
Mariana da Silva Castro
Dalmo Valério Machado de Lima
author_facet Aretha Pereira de Oliveira
Mariana da Silva Castro
Dalmo Valério Machado de Lima
author_sort Aretha Pereira de Oliveira
collection DOAJ
description ABSTRACT Objective: This study aimed to investigate the association between glycemic variability and mortality in patients admitted to oncologic intensive care units. Methods: A retrospective cohort study was conducted using a convenience sample of 30 medical records of patients over 18 years of age of both sexes. Glycemic variability was measured using the standard deviation and general amplitude. Statistical analysis was performed using the receiver operating characteristic (ROC) curve and the area under the curve (AUC). The significance level (α) was set at 5% with a confidence interval (CI) of 95%. Results: The study included 14 male patients (46.67%) with a mean age of 60±15 years. A total of 1503 blood glucose samples were collected. The AUC analysis for the standard deviation did not show a statistically significant result (p=.966; 95% CI=[0.283, 0.726]). In contrast, the general amplitude had a statistically significant association with mortality (p=.049; 95% CI=[0.514, 0.916]). Conclusions: This study found that glycemic variability measured by the general amplitude was significantly associated with patient mortality in oncologic intensive care units. These findings suggest that monitoring glycemic variability may be an important factor in the management of critically ill patients in oncologic intensive care units.
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spelling doaj.art-0202b73937904d43b8555e74877e57652023-10-10T07:43:34ZengAssociação Brasileira de EnfermagemRevista Brasileira de Enfermagem1984-04462023-10-0176410.1590/0034-7167-2022-0812Glycemic variability and mortality in oncologic intensive care unitsAretha Pereira de Oliveirahttps://orcid.org/0000-0003-1549-7729Mariana da Silva Castrohttps://orcid.org/0000-0002-5183-1803Dalmo Valério Machado de Limahttps://orcid.org/0000-0003-3587-6224ABSTRACT Objective: This study aimed to investigate the association between glycemic variability and mortality in patients admitted to oncologic intensive care units. Methods: A retrospective cohort study was conducted using a convenience sample of 30 medical records of patients over 18 years of age of both sexes. Glycemic variability was measured using the standard deviation and general amplitude. Statistical analysis was performed using the receiver operating characteristic (ROC) curve and the area under the curve (AUC). The significance level (α) was set at 5% with a confidence interval (CI) of 95%. Results: The study included 14 male patients (46.67%) with a mean age of 60±15 years. A total of 1503 blood glucose samples were collected. The AUC analysis for the standard deviation did not show a statistically significant result (p=.966; 95% CI=[0.283, 0.726]). In contrast, the general amplitude had a statistically significant association with mortality (p=.049; 95% CI=[0.514, 0.916]). Conclusions: This study found that glycemic variability measured by the general amplitude was significantly associated with patient mortality in oncologic intensive care units. These findings suggest that monitoring glycemic variability may be an important factor in the management of critically ill patients in oncologic intensive care units.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71672023000800223&lng=en&tlng=enIntensive Care UnitsBlood GlucoseMortalityNeoplasmsGlycemic Control.
spellingShingle Aretha Pereira de Oliveira
Mariana da Silva Castro
Dalmo Valério Machado de Lima
Glycemic variability and mortality in oncologic intensive care units
Revista Brasileira de Enfermagem
Intensive Care Units
Blood Glucose
Mortality
Neoplasms
Glycemic Control.
title Glycemic variability and mortality in oncologic intensive care units
title_full Glycemic variability and mortality in oncologic intensive care units
title_fullStr Glycemic variability and mortality in oncologic intensive care units
title_full_unstemmed Glycemic variability and mortality in oncologic intensive care units
title_short Glycemic variability and mortality in oncologic intensive care units
title_sort glycemic variability and mortality in oncologic intensive care units
topic Intensive Care Units
Blood Glucose
Mortality
Neoplasms
Glycemic Control.
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71672023000800223&lng=en&tlng=en
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AT dalmovaleriomachadodelima glycemicvariabilityandmortalityinoncologicintensivecareunits