A critical bioenergetic switch is regulated by IGF2 during murine cartilage development

A critical bioenergetic switch is regulated by IGF2 during murine cartilage development

Murine chondrocyte hypertrophy was found to require IGF2-regulated bioenergetic reprogramming, in which glucose utilization shifts from glycolysis to oxidative phosphorylation as chondrocytes mature.

Bibliographic Details
Main Authors:	Judith M. Hollander, Lingyun Li, Miraj Rawal, Si Kun Wang, Yue Shu, Ming Zhang, Heber C. Nielsen, Clifford J. Rosen, Li Zeng
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-11-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-022-04156-4

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