Annexin A1 May Induce Pancreatic Cancer Progression as a Key Player of Extracellular Vesicles Effects as Evidenced in the <i>In Vitro</i> MIA PaCa-2 Model System

Annexin A1 May Induce Pancreatic Cancer Progression as a Key Player of Extracellular Vesicles Effects as Evidenced in the <i>In Vitro</i> MIA PaCa-2 Model System

Pancreatic Cancer (PC) is one of the most aggressive malignancies worldwide. As annexin A1 (ANXA1) is implicated in the establishment of tumour metastasis, the role of the protein in PC progression as a component of extracellular vesicles (EVs) has been investigated. EVs were isolated from wild type...

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Bibliographic Details
Main Authors: Emanuela Pessolano, Raffaella Belvedere, Valentina Bizzarro, Paola Franco, Iolanda De Marco, Amalia Porta, Alessandra Tosco, Luca Parente, Mauro Perretti, Antonello Petrella
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
Annexin A1
EVs
pancreatic cancer
CRISPR/Cas9 genome editing technique
epithelial to mesenchymal transition
Online Access:https://www.mdpi.com/1422-0067/19/12/3878

Internet

https://www.mdpi.com/1422-0067/19/12/3878

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