Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism
The application of nano-Ag grains as antiviral and antibacterial materials is widely known since ancient times. The problem is the toxicity of the bulk or big-size grain materials. It is known that nano-sized silver grains affect human and animal cells in some medical treatments. The aim of this stu...
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| Format: | Article |
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| Online Access: | https://www.mdpi.com/1996-1944/15/17/5826 |
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| author | Sylwia Terpilowska Stanislaw Gluszek Elzbieta Czerwosz Halina Wronka Piotr Firek Jan Szmidt Malgorzata Suchanska Justyna Keczkowska Bozena Kaczmarska Mirosław Kozlowski Ryszard Diduszko |
| author_facet | Sylwia Terpilowska Stanislaw Gluszek Elzbieta Czerwosz Halina Wronka Piotr Firek Jan Szmidt Malgorzata Suchanska Justyna Keczkowska Bozena Kaczmarska Mirosław Kozlowski Ryszard Diduszko |
| author_sort | Sylwia Terpilowska |
| collection | DOAJ |
| description | The application of nano-Ag grains as antiviral and antibacterial materials is widely known since ancient times. The problem is the toxicity of the bulk or big-size grain materials. It is known that nano-sized silver grains affect human and animal cells in some medical treatments. The aim of this study is to investigate the influence of nano-Ag grains embedded in a carbonaceous matrix on cytotoxicity, genotoxicity in fibroblasts, and mutagenicity. The nanocomposite film is composed of silver nanograins embedded in a carbonaceous matrix and it was obtained via the PVD method by deposition from two separated sources of fullerenes and silver acetate powders. This method allows for the preparation of material in the form of a film or powder, in which Ag nanograins are stabilized by a carbon network. The structure and morphology of this material were studied using SEM/EDX, XRD, and Raman spectroscopy. The toxicology studies were performed for various types of the material differing in the size of Ag nanograins. Furthermore, it was found that these properties, such as cell viability, genotoxicity, and mutagenicity, depend on Ag grain size. |
| first_indexed | 2024-03-10T01:37:03Z |
| format | Article |
| id | doaj.art-020726ac087f4f40beb122491393e541 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T01:37:03Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-020726ac087f4f40beb122491393e5412023-11-23T13:30:49ZengMDPI AGMaterials1996-19442022-08-011517582610.3390/ma15175826Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell MetabolismSylwia Terpilowska0Stanislaw Gluszek1Elzbieta Czerwosz2Halina Wronka3Piotr Firek4Jan Szmidt5Malgorzata Suchanska6Justyna Keczkowska7Bozena Kaczmarska8Mirosław Kozlowski9Ryszard Diduszko10Jan Kochanowski University, Collegium Medicum, Department of Surgical Medicine with the Laboratory of Medical Genetics, IX Wieków Kielc 19A Av., 25-317 Kielce, PolandJan Kochanowski University, Collegium Medicum, Department of Surgical Medicine with the Laboratory of Medical Genetics, IX Wieków Kielc 19A Av., 25-317 Kielce, PolandInstitute of Micro- and OptoElectronics, Warsaw Technical University, Nowowiejska 15/19, 00-665 Warszawa, PolandInstitute of Micro- and OptoElectronics, Warsaw Technical University, Nowowiejska 15/19, 00-665 Warszawa, PolandInstitute of Micro- and OptoElectronics, Warsaw Technical University, Nowowiejska 15/19, 00-665 Warszawa, PolandInstitute of Micro- and OptoElectronics, Warsaw Technical University, Nowowiejska 15/19, 00-665 Warszawa, PolandKielce University of Technology, Al. Tysiąclecia Państwa Polskiego 7, 25-314 Kielce, PolandKielce University of Technology, Al. Tysiąclecia Państwa Polskiego 7, 25-314 Kielce, PolandKielce University of Technology, Al. Tysiąclecia Państwa Polskiego 7, 25-314 Kielce, PolandŁukasiewicz Research Network, Tele and Radio Research Institute, ul. Ratuszowa 11, 03-450 Warszawa, PolandŁukasiewicz Research Network, Institute of Microelectronics and Photonics, ul. Wólczyńskiej 133, 01-919 Warszawa, PolandThe application of nano-Ag grains as antiviral and antibacterial materials is widely known since ancient times. The problem is the toxicity of the bulk or big-size grain materials. It is known that nano-sized silver grains affect human and animal cells in some medical treatments. The aim of this study is to investigate the influence of nano-Ag grains embedded in a carbonaceous matrix on cytotoxicity, genotoxicity in fibroblasts, and mutagenicity. The nanocomposite film is composed of silver nanograins embedded in a carbonaceous matrix and it was obtained via the PVD method by deposition from two separated sources of fullerenes and silver acetate powders. This method allows for the preparation of material in the form of a film or powder, in which Ag nanograins are stabilized by a carbon network. The structure and morphology of this material were studied using SEM/EDX, XRD, and Raman spectroscopy. The toxicology studies were performed for various types of the material differing in the size of Ag nanograins. Furthermore, it was found that these properties, such as cell viability, genotoxicity, and mutagenicity, depend on Ag grain size.https://www.mdpi.com/1996-1944/15/17/5826genotoxicitymutagenicitycytotoxicitynanocomposite nano-Ag |
| spellingShingle | Sylwia Terpilowska Stanislaw Gluszek Elzbieta Czerwosz Halina Wronka Piotr Firek Jan Szmidt Malgorzata Suchanska Justyna Keczkowska Bozena Kaczmarska Mirosław Kozlowski Ryszard Diduszko Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism Materials genotoxicity mutagenicity cytotoxicity nanocomposite nano-Ag |
| title | Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism |
| title_full | Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism |
| title_fullStr | Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism |
| title_full_unstemmed | Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism |
| title_short | Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism |
| title_sort | nano ag particles embedded in c matrix preparation properties and application in cell metabolism |
| topic | genotoxicity mutagenicity cytotoxicity nanocomposite nano-Ag |
| url | https://www.mdpi.com/1996-1944/15/17/5826 |
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