Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model

Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model

Abstract Background MicroRNAs (miRNAs) are important post-transcriptional gene regulators controlling cellular lineage specification and differentiation during embryonic development, including the gastrointestinal system. However, miRNA-mediated regulatory mechanisms involved in early embryonic deve...

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Bibliographic Details
Main Authors: Yu-Han Hung, Meghan Capeling, Jonathan W. Villanueva, Matt Kanke, Michael T. Shanahan, Sha Huang, Rebecca Cubitt, Vera D. Rinaldi, John C. Schimenti, Jason R. Spence, Praveen Sethupathy
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Genomics
Subjects:
Micro-RNA
Post-transcriptional regulation
Intestine
Development
Functional genomics
Online Access:https://doi.org/10.1186/s12864-023-09743-1

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