Pharmacology of caffeine and its effects on the human body
Caffeine is the world's most popular stimulant and psychoactive substance. Given the ubiquitous use of caffeine, it is crucial for us to comprehend how our body interacts with caffeine. The pharmacokinetics of caffeine and its action mechanisms have been reviewed in this paper. The safety and r...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | European Journal of Medicinal Chemistry Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417424000104 |
| _version_ | 1797262756364156928 |
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| author | Vundrala Sumedha Reddy S. Shiva Srinidhi Manikantan Seeram Ramakrishna |
| author_facet | Vundrala Sumedha Reddy S. Shiva Srinidhi Manikantan Seeram Ramakrishna |
| author_sort | Vundrala Sumedha Reddy |
| collection | DOAJ |
| description | Caffeine is the world's most popular stimulant and psychoactive substance. Given the ubiquitous use of caffeine, it is crucial for us to comprehend how our body interacts with caffeine. The pharmacokinetics of caffeine and its action mechanisms have been reviewed in this paper. The safety and recommended dosage of caffeine in healthy adults and vulnerable populations like children and pregnant women are also discussed in this paper. While caffeine consumption is generally safe, this review paper also examines the potential effects that caffeine could have on human health and development. Studies indicated that caffeine exhibits neuroprotective properties, potentially serving as a preventive measure against the onset of neurodegenerative conditions such as Alzheimer's and Parkinson's disease. The article also explores various physiological effects of caffeine on the body, in addition to investigating novel drug delivery techniques, particularly nano-delivery systems designed to efficiently administer caffeine. |
| first_indexed | 2024-03-07T16:52:40Z |
| format | Article |
| id | doaj.art-02088198b0a349948ef3813193ae96bb |
| institution | Directory Open Access Journal |
| issn | 2772-4174 |
| language | English |
| last_indexed | 2024-04-25T00:02:10Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | European Journal of Medicinal Chemistry Reports |
| spelling | doaj.art-02088198b0a349948ef3813193ae96bb2024-03-14T06:17:06ZengElsevierEuropean Journal of Medicinal Chemistry Reports2772-41742024-04-0110100138Pharmacology of caffeine and its effects on the human bodyVundrala Sumedha Reddy0S. Shiva1Srinidhi Manikantan2Seeram Ramakrishna3Centre for Nanotechnology & Sustainability, Department of Mechanical Engineering, National University of Singapore, Singapore, 117574, Singapore; Corresponding author.Centre for Nanotechnology & Sustainability, Department of Mechanical Engineering, National University of Singapore, Singapore, 117574, Singapore; School of Bioscience and Technology, Vellore Institute of Technology, Vellore, 632014, IndiaCentre for Nanotechnology & Sustainability, Department of Mechanical Engineering, National University of Singapore, Singapore, 117574, SingaporeCentre for Nanotechnology & Sustainability, Department of Mechanical Engineering, National University of Singapore, Singapore, 117574, SingaporeCaffeine is the world's most popular stimulant and psychoactive substance. Given the ubiquitous use of caffeine, it is crucial for us to comprehend how our body interacts with caffeine. The pharmacokinetics of caffeine and its action mechanisms have been reviewed in this paper. The safety and recommended dosage of caffeine in healthy adults and vulnerable populations like children and pregnant women are also discussed in this paper. While caffeine consumption is generally safe, this review paper also examines the potential effects that caffeine could have on human health and development. Studies indicated that caffeine exhibits neuroprotective properties, potentially serving as a preventive measure against the onset of neurodegenerative conditions such as Alzheimer's and Parkinson's disease. The article also explores various physiological effects of caffeine on the body, in addition to investigating novel drug delivery techniques, particularly nano-delivery systems designed to efficiently administer caffeine.http://www.sciencedirect.com/science/article/pii/S2772417424000104CaffeinePharmacological effectsPharmacokineticsMechanismPregnancyDrug delivery |
| spellingShingle | Vundrala Sumedha Reddy S. Shiva Srinidhi Manikantan Seeram Ramakrishna Pharmacology of caffeine and its effects on the human body European Journal of Medicinal Chemistry Reports Caffeine Pharmacological effects Pharmacokinetics Mechanism Pregnancy Drug delivery |
| title | Pharmacology of caffeine and its effects on the human body |
| title_full | Pharmacology of caffeine and its effects on the human body |
| title_fullStr | Pharmacology of caffeine and its effects on the human body |
| title_full_unstemmed | Pharmacology of caffeine and its effects on the human body |
| title_short | Pharmacology of caffeine and its effects on the human body |
| title_sort | pharmacology of caffeine and its effects on the human body |
| topic | Caffeine Pharmacological effects Pharmacokinetics Mechanism Pregnancy Drug delivery |
| url | http://www.sciencedirect.com/science/article/pii/S2772417424000104 |
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