Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review

Abstract Mechanical ventilation is a lifesaving treatment used to treat critical neonatal patients. It facilitates gas exchange, oxygenation, and CO2 removal. Despite advances in non-invasive ventilatory support methods in neonates, invasive ventilation (i.e., ventilation via an endotracheal tube) i...

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Main Authors: Razieh Sangsari, Maryam Saeedi, Marzieh Maddah, Kayvan Mirnia, Jay P. Goldsmith
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-022-02223-4
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author Razieh Sangsari
Maryam Saeedi
Marzieh Maddah
Kayvan Mirnia
Jay P. Goldsmith
author_facet Razieh Sangsari
Maryam Saeedi
Marzieh Maddah
Kayvan Mirnia
Jay P. Goldsmith
author_sort Razieh Sangsari
collection DOAJ
description Abstract Mechanical ventilation is a lifesaving treatment used to treat critical neonatal patients. It facilitates gas exchange, oxygenation, and CO2 removal. Despite advances in non-invasive ventilatory support methods in neonates, invasive ventilation (i.e., ventilation via an endotracheal tube) is still a standard treatment in NICUs. This ventilation approach may cause injury despite its advantages, especially in preterm neonates. Therefore, it is recommended that neonatologists consider weaning neonates from invasive mechanical ventilation as soon as possible. This review examines the steps required for the neonate's appropriate weaning and safe extubation from mechanical ventilation.
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spelling doaj.art-020d2ca12a9f430bb6c5fc2a274e34e72022-12-22T04:39:00ZengBMCBMC Pulmonary Medicine1471-24662022-11-0122111210.1186/s12890-022-02223-4Weaning and extubation from neonatal mechanical ventilation: an evidenced-based reviewRazieh Sangsari0Maryam Saeedi1Marzieh Maddah2Kayvan Mirnia3Jay P. Goldsmith4Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Tehran University of Medical Sciences, Children’s Medical Center, Pediatric Center of ExcellenceDepartment of Pediatrics, Division of Neonatology, Faculty of Medicine, Tehran University of Medical Sciences, Children’s Medical Center, Pediatric Center of ExcellenceDepartment of Pediatrics, Division of Neonatology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Shohadaye Tajrish HospitalDepartment of Pediatrics, Division of Neonatology, Faculty of Medicine, Tehran University of Medical Sciences, Children’s Medical Center, Pediatric Center of ExcellenceDivision of Newborn Medicine, Tulane University School of MedicineAbstract Mechanical ventilation is a lifesaving treatment used to treat critical neonatal patients. It facilitates gas exchange, oxygenation, and CO2 removal. Despite advances in non-invasive ventilatory support methods in neonates, invasive ventilation (i.e., ventilation via an endotracheal tube) is still a standard treatment in NICUs. This ventilation approach may cause injury despite its advantages, especially in preterm neonates. Therefore, it is recommended that neonatologists consider weaning neonates from invasive mechanical ventilation as soon as possible. This review examines the steps required for the neonate's appropriate weaning and safe extubation from mechanical ventilation.https://doi.org/10.1186/s12890-022-02223-4Non-invasive ventilationInfantAirway extubationVentilator weaning
spellingShingle Razieh Sangsari
Maryam Saeedi
Marzieh Maddah
Kayvan Mirnia
Jay P. Goldsmith
Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review
BMC Pulmonary Medicine
Non-invasive ventilation
Infant
Airway extubation
Ventilator weaning
title Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review
title_full Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review
title_fullStr Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review
title_full_unstemmed Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review
title_short Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review
title_sort weaning and extubation from neonatal mechanical ventilation an evidenced based review
topic Non-invasive ventilation
Infant
Airway extubation
Ventilator weaning
url https://doi.org/10.1186/s12890-022-02223-4
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