Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature

The use of Calotropis plant is widespread in the Indian system of Medicine (Ayurveda) and for religious purpose as an offering to Hindu god. Having an advantage of growing abundantly in unfavorable and harsh atmosphere, this shrub is easily found in many Indian states. We report here a case, in whic...

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Main Authors: Vaibhav Kumar Jain, Divya Kesarwani, Vishal Yadav, Kumudini Sharma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:TNOA Journal of Ophthalmic Science and Research
Subjects:
Online Access:http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2020;volume=58;issue=1;spage=37;epage=39;aulast=Jain
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author Vaibhav Kumar Jain
Divya Kesarwani
Vishal Yadav
Kumudini Sharma
author_facet Vaibhav Kumar Jain
Divya Kesarwani
Vishal Yadav
Kumudini Sharma
author_sort Vaibhav Kumar Jain
collection DOAJ
description The use of Calotropis plant is widespread in the Indian system of Medicine (Ayurveda) and for religious purpose as an offering to Hindu god. Having an advantage of growing abundantly in unfavorable and harsh atmosphere, this shrub is easily found in many Indian states. We report here a case, in which a young boy developed severe corneal edema in both eyes following the application of Calotropis latex over the scalp area for the treatment of alopecia as prescribed by some Ayurveda practitioner. Patient responded well with the treatment including topical steroids with a complete resolution of corneal edema and persistent endothelial cell loss at the end of 6 weeks. This case report highlights the possibility of Calotropis-induced corneal endothelial toxicity while using it as an Ayurveda remedy and its management. Public education is must regarding this particularly in India where the use and availability of Calotropis shrub is widespread.
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spelling doaj.art-020dea08a71644ff96f6f1852e3771702022-12-22T02:41:33ZengWolters Kluwer Medknow PublicationsTNOA Journal of Ophthalmic Science and Research2589-45282589-45362020-01-01581373910.4103/tjosr.tjosr_95_19Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literatureVaibhav Kumar JainDivya KesarwaniVishal YadavKumudini SharmaThe use of Calotropis plant is widespread in the Indian system of Medicine (Ayurveda) and for religious purpose as an offering to Hindu god. Having an advantage of growing abundantly in unfavorable and harsh atmosphere, this shrub is easily found in many Indian states. We report here a case, in which a young boy developed severe corneal edema in both eyes following the application of Calotropis latex over the scalp area for the treatment of alopecia as prescribed by some Ayurveda practitioner. Patient responded well with the treatment including topical steroids with a complete resolution of corneal edema and persistent endothelial cell loss at the end of 6 weeks. This case report highlights the possibility of Calotropis-induced corneal endothelial toxicity while using it as an Ayurveda remedy and its management. Public education is must regarding this particularly in India where the use and availability of Calotropis shrub is widespread.http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2020;volume=58;issue=1;spage=37;epage=39;aulast=Jainayurveda medicinecalotropis proceracorneal toxicityendothelial toxicitymadar
spellingShingle Vaibhav Kumar Jain
Divya Kesarwani
Vishal Yadav
Kumudini Sharma
Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature
TNOA Journal of Ophthalmic Science and Research
ayurveda medicine
calotropis procera
corneal toxicity
endothelial toxicity
madar
title Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature
title_full Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature
title_fullStr Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature
title_full_unstemmed Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature
title_short Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature
title_sort calotropis induced corneal toxicity in indian medicinal use a rare case report with review of literature
topic ayurveda medicine
calotropis procera
corneal toxicity
endothelial toxicity
madar
url http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2020;volume=58;issue=1;spage=37;epage=39;aulast=Jain
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AT divyakesarwani calotropisinducedcornealtoxicityinindianmedicinaluseararecasereportwithreviewofliterature
AT vishalyadav calotropisinducedcornealtoxicityinindianmedicinaluseararecasereportwithreviewofliterature
AT kumudinisharma calotropisinducedcornealtoxicityinindianmedicinaluseararecasereportwithreviewofliterature