Mild Crigler–Najjar Syndrome with Progressive Liver Disease—A Multicenter Retrospective Cohort Study

Mild Crigler–Najjar Syndrome with Progressive Liver Disease—A Multicenter Retrospective Cohort Study

Crigler–Najjar Syndrome (CNS) with residual activity of UDP-glucuronosyltransferase 1A1 (<i>UGT1A1</i>) and no need for daily phototherapy is called mild Crigler–Najjar Syndrome. Most of these patients need medical treatment for enzyme induction (phenobarbital) to lower blood levels of u...

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Bibliographic Details
Main Authors: Norman Junge, Hanna Hentschel, Dorothee Krebs-Schmitt, Amelie Stalke, Eva-Doreen Pfister, Björn Hartleben, Martin Claßen, Alexander Querfurt, Veronika Münch, Philip Bufler, Jun Oh, Enke Grabhorn
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Children
Subjects:
liver fibrosis
liver transplantation
Gilbert syndrome
hyperbilirubinemia
UGT1A1
phototherapy
Online Access:https://www.mdpi.com/2227-9067/10/9/1431

Internet

https://www.mdpi.com/2227-9067/10/9/1431

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