Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium
Abstract Purpose: To assess the autofluorescence size and properties of pterygium and pinguecula by anterior segment autofluorescence (AS-AF) imaging and demonstrate the difference of autofluorescence size presented in AS-AF imaging compared to the extend size of the conjunctival lesion measured by...
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| Format: | Article |
| Language: | English |
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Knowledge E
2023-07-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | https://doi.org/10.18502/jovr.v18i3.13773 |
| _version_ | 1797743282597396480 |
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| author | Amir-Hooshang Beheshtnejad Hamed Ghassemi Hossein Abdolkhalegh Mehrnaz Atighehchian |
| author_facet | Amir-Hooshang Beheshtnejad Hamed Ghassemi Hossein Abdolkhalegh Mehrnaz Atighehchian |
| author_sort | Amir-Hooshang Beheshtnejad |
| collection | DOAJ |
| description | Abstract Purpose: To assess the autofluorescence size and properties of pterygium and pinguecula by anterior segment autofluorescence (AS-AF) imaging and demonstrate the difference of autofluorescence size presented in AS-AF imaging compared to the extend size of the conjunctival lesion measured by anterior segment slit-lamp photography (AS-SLE). Methods: Twenty-five patients with primary pterygium and twenty-five with pinguecula were included in the study. In addition, 25 normal subjects were also enrolled as the control group. The AS-AF characteristics of pterygium and pinguecula lesions were analyzed. The size of lesions displayed in the AS-SLE photography versus the AS-AF images were also compared. AS-AF images were obtained using a Heidelberg retina angiograph which focused on the anterior segment. AS-SLE photography was acquired using a digital imaging system (BX900 HAAG-STREIT). Results: There were 44 (58.7%) male and 31 (41.3%) female patients; 19 (76%) and 20 (80%) patients had bilateral pterygium and pinguecula, respectively. All pinguecula lesions reflected hyperautofluorescence pattern in the AS-AF imaging. In 24 (96%) patients, the hyperautofluoresecence pattern was larger than the size of the clinical lesions displayed with the AS-SLE photography. Twenty-one (84%) patients with pterygium reflected a hyperautofluorescence pattern in AS-AF images; in one (4%) patient, the hyperautofluorescence pattern was larger than the clinical lesion size and four (16%) patients had no autofluorescence patterns in the AS-AF images. In the control group, in 14 (56%) subjects, a hypoautofluorescent pattern was revealed in the conjunctiva in AS-AF images. However, in 11 (44%) patients, hyperautofluorescence patterns were detected. Conclusion: AS-AF is a useful modality to monitor vascularization in conjunctival lesions. Pingueculae and pterygium show hyperautofluorescence in AS-AF imaging. The real size of the pinguecula lesions may be estimated with AS-AF characteristics, mostly presenting larger than the area size in AS-SLE photography. The autofluorescence size of the pterygium is smaller than the extent of visible pterygium in slit-lamp photography. |
| first_indexed | 2024-03-12T14:53:15Z |
| format | Article |
| id | doaj.art-021185c56cc94a3baa924f17a9ac7cb7 |
| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-03-12T14:53:15Z |
| publishDate | 2023-07-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-021185c56cc94a3baa924f17a9ac7cb72023-08-15T05:44:01ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2023-07-0118326026610.18502/jovr.v18i3.13773jovr.v18i3.13773Clinical and Autofluorescence Findings in Eyes with Pinguecula and PterygiumAmir-Hooshang Beheshtnejad0Hamed Ghassemi1Hossein Abdolkhalegh2Mehrnaz Atighehchian3 Department of Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranAbstract Purpose: To assess the autofluorescence size and properties of pterygium and pinguecula by anterior segment autofluorescence (AS-AF) imaging and demonstrate the difference of autofluorescence size presented in AS-AF imaging compared to the extend size of the conjunctival lesion measured by anterior segment slit-lamp photography (AS-SLE). Methods: Twenty-five patients with primary pterygium and twenty-five with pinguecula were included in the study. In addition, 25 normal subjects were also enrolled as the control group. The AS-AF characteristics of pterygium and pinguecula lesions were analyzed. The size of lesions displayed in the AS-SLE photography versus the AS-AF images were also compared. AS-AF images were obtained using a Heidelberg retina angiograph which focused on the anterior segment. AS-SLE photography was acquired using a digital imaging system (BX900 HAAG-STREIT). Results: There were 44 (58.7%) male and 31 (41.3%) female patients; 19 (76%) and 20 (80%) patients had bilateral pterygium and pinguecula, respectively. All pinguecula lesions reflected hyperautofluorescence pattern in the AS-AF imaging. In 24 (96%) patients, the hyperautofluoresecence pattern was larger than the size of the clinical lesions displayed with the AS-SLE photography. Twenty-one (84%) patients with pterygium reflected a hyperautofluorescence pattern in AS-AF images; in one (4%) patient, the hyperautofluorescence pattern was larger than the clinical lesion size and four (16%) patients had no autofluorescence patterns in the AS-AF images. In the control group, in 14 (56%) subjects, a hypoautofluorescent pattern was revealed in the conjunctiva in AS-AF images. However, in 11 (44%) patients, hyperautofluorescence patterns were detected. Conclusion: AS-AF is a useful modality to monitor vascularization in conjunctival lesions. Pingueculae and pterygium show hyperautofluorescence in AS-AF imaging. The real size of the pinguecula lesions may be estimated with AS-AF characteristics, mostly presenting larger than the area size in AS-SLE photography. The autofluorescence size of the pterygium is smaller than the extent of visible pterygium in slit-lamp photography.https://doi.org/10.18502/jovr.v18i3.13773autofluorescencepingueculapterygium |
| spellingShingle | Amir-Hooshang Beheshtnejad Hamed Ghassemi Hossein Abdolkhalegh Mehrnaz Atighehchian Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium Journal of Ophthalmic & Vision Research autofluorescence pinguecula pterygium |
| title | Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium |
| title_full | Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium |
| title_fullStr | Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium |
| title_full_unstemmed | Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium |
| title_short | Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium |
| title_sort | clinical and autofluorescence findings in eyes with pinguecula and pterygium |
| topic | autofluorescence pinguecula pterygium |
| url | https://doi.org/10.18502/jovr.v18i3.13773 |
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