Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies
ObjectiveThis study aimed to summarize the effectiveness of rhythmic auditory stimulation (RAS) for the treatment of gait and motor function in Parkinson's disease (PD) through a systematic review and meta-analysis.MethodsAll studies were retrieved from eight databases. The effects of RAS on PD...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.818559/full |
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| author | Lei Wang Jin-lin Peng Jian-bin Ou-Yang Li Gan Shuai Zeng Hong-Yan Wang Guan-Chao Zuo Ling Qiu |
| author_facet | Lei Wang Jin-lin Peng Jian-bin Ou-Yang Li Gan Shuai Zeng Hong-Yan Wang Guan-Chao Zuo Ling Qiu |
| author_sort | Lei Wang |
| collection | DOAJ |
| description | ObjectiveThis study aimed to summarize the effectiveness of rhythmic auditory stimulation (RAS) for the treatment of gait and motor function in Parkinson's disease (PD) through a systematic review and meta-analysis.MethodsAll studies were retrieved from eight databases. The effects of RAS on PD were determined using the following indicators: gait parameters including step length, stride width, step cadence, velocity, stride length; motor function including 6 min walk test (6MWT) and timed up-and-go test (TUGT); the Unified Parkinson's Disease Rating Scale (UPDRS); and the Berg Balance Scale (BBS). The risk map of bias of the quality of the studies and the meta-analysis results of the indicators was prepared with RevMan 5.2 software.ResultsTwenty-one studies were included in the systematic review, and 14 studies were included in the meta-analysis. In the meta-analysis, the results of gait parameters, namely, velocity, step length, and stride length, were statistically significant (P < 0.05), whereas the results of cadence and stride width were not statistically significant (P ≧ 0.05). The results of 6MWT and TUGT for motor function as well as UPDRS-II, UPDRS-III, and BBS were statistically significant (P < 0.05).ConclusionsRAS could improve gait parameters, walking function, balance function, and daily living activities of individuals with PD. The application of RAS in conventional rehabilitation approaches can enhance motor performance in PD. Future studies should use a large sample size and a rigorous design to obtain strong conclusions about the advantages of RAS for the treatment of gait and motor function in PD. |
| first_indexed | 2024-04-14T00:31:39Z |
| format | Article |
| id | doaj.art-02136f071ad34ba09e502049df1e4d5f |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-14T00:31:39Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-02136f071ad34ba09e502049df1e4d5f2022-12-22T02:22:31ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-04-011310.3389/fneur.2022.818559818559Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled StudiesLei Wang0Jin-lin Peng1Jian-bin Ou-Yang2Li Gan3Shuai Zeng4Hong-Yan Wang5Guan-Chao Zuo6Ling Qiu7Department of Rehabilitation Medicine, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, ChinaTongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Pain, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu, ChinaSichuan Rehabilitation Hospital Affiliated of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Pain, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu, ChinaSichuan Rehabilitation Hospital Affiliated of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSichuan Rehabilitation Hospital Affiliated of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Pain, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu, ChinaObjectiveThis study aimed to summarize the effectiveness of rhythmic auditory stimulation (RAS) for the treatment of gait and motor function in Parkinson's disease (PD) through a systematic review and meta-analysis.MethodsAll studies were retrieved from eight databases. The effects of RAS on PD were determined using the following indicators: gait parameters including step length, stride width, step cadence, velocity, stride length; motor function including 6 min walk test (6MWT) and timed up-and-go test (TUGT); the Unified Parkinson's Disease Rating Scale (UPDRS); and the Berg Balance Scale (BBS). The risk map of bias of the quality of the studies and the meta-analysis results of the indicators was prepared with RevMan 5.2 software.ResultsTwenty-one studies were included in the systematic review, and 14 studies were included in the meta-analysis. In the meta-analysis, the results of gait parameters, namely, velocity, step length, and stride length, were statistically significant (P < 0.05), whereas the results of cadence and stride width were not statistically significant (P ≧ 0.05). The results of 6MWT and TUGT for motor function as well as UPDRS-II, UPDRS-III, and BBS were statistically significant (P < 0.05).ConclusionsRAS could improve gait parameters, walking function, balance function, and daily living activities of individuals with PD. The application of RAS in conventional rehabilitation approaches can enhance motor performance in PD. Future studies should use a large sample size and a rigorous design to obtain strong conclusions about the advantages of RAS for the treatment of gait and motor function in PD.https://www.frontiersin.org/articles/10.3389/fneur.2022.818559/fullparkinsonismrhythmic auditory stimulationRASmeta-analysisParkinson's |
| spellingShingle | Lei Wang Jin-lin Peng Jian-bin Ou-Yang Li Gan Shuai Zeng Hong-Yan Wang Guan-Chao Zuo Ling Qiu Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies Frontiers in Neurology parkinsonism rhythmic auditory stimulation RAS meta-analysis Parkinson's |
| title | Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies |
| title_full | Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies |
| title_fullStr | Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies |
| title_full_unstemmed | Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies |
| title_short | Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies |
| title_sort | effects of rhythmic auditory stimulation on gait and motor function in parkinson s disease a systematic review and meta analysis of clinical randomized controlled studies |
| topic | parkinsonism rhythmic auditory stimulation RAS meta-analysis Parkinson's |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.818559/full |
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