Head and neck soft tissue sarcomas treated with radiation therapy
Head and neck soft tissue sarcomas (HNSTSs) are rare and heterogeneous cancers in which radiation therapy (RT) has an important role in local tumor control (LC). The purpose of this study was to evaluate outcomes and patterns of treatment failure in patients with HNSTS treated with RT. A retrospecti...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2016-06-01
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| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/6165 |
| _version_ | 1828761456514957312 |
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| author | Lucas K. Vitzthum Lindsay B. Brown Jessica W. Rooney Robert L. Foote |
| author_facet | Lucas K. Vitzthum Lindsay B. Brown Jessica W. Rooney Robert L. Foote |
| author_sort | Lucas K. Vitzthum |
| collection | DOAJ |
| description | Head and neck soft tissue sarcomas (HNSTSs) are rare and heterogeneous cancers in which radiation therapy (RT) has an important role in local tumor control (LC). The purpose of this study was to evaluate outcomes and patterns of treatment failure in patients with HNSTS treated with RT. A retrospective review was performed of adult patients with HNSTS treated with RT from January 1, 1998, to December 31, 2012. LC, locoregional control (LRC), disease-free survival (DFS), overall survival (OS), and predictors thereof were assessed. Forty-eight patients with HNSTS were evaluated. Five-year Kaplan-Meier estimates of LC, LRC, DFS, and OS were 87, 73, 63, and 83%, respectively. Angiosarcomas were found to be associated with worse LC, LRC, DFS, and OS. Patients over the age of 60 had lower rates of DFS. HNSTSs comprise a diverse group of tumors that can be managed with various treatment regimens involving RT. Angiosarcomas have higher recurrence and mortality rates. |
| first_indexed | 2024-12-11T01:30:26Z |
| format | Article |
| id | doaj.art-0213bd5f451b419dbc7342b82a8e4f66 |
| institution | Directory Open Access Journal |
| issn | 2036-3605 2036-3613 |
| language | English |
| last_indexed | 2024-12-11T01:30:26Z |
| publishDate | 2016-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-0213bd5f451b419dbc7342b82a8e4f662022-12-22T01:25:23ZengSAGE PublishingRare Tumors2036-36052036-36132016-06-018210.4081/rt.2016.61653367Head and neck soft tissue sarcomas treated with radiation therapyLucas K. Vitzthum0Lindsay B. Brown1Jessica W. Rooney2Robert L. Foote3Mayo Clinic College of Medicine, Rochester, MNDepartment of Radiation Oncology, Mayo Clinic, Rochester, MNDepartment of Radiation Oncology, Mayo Clinic, Rochester, MNDepartment of Radiation Oncology, Mayo Clinic, Rochester, MNHead and neck soft tissue sarcomas (HNSTSs) are rare and heterogeneous cancers in which radiation therapy (RT) has an important role in local tumor control (LC). The purpose of this study was to evaluate outcomes and patterns of treatment failure in patients with HNSTS treated with RT. A retrospective review was performed of adult patients with HNSTS treated with RT from January 1, 1998, to December 31, 2012. LC, locoregional control (LRC), disease-free survival (DFS), overall survival (OS), and predictors thereof were assessed. Forty-eight patients with HNSTS were evaluated. Five-year Kaplan-Meier estimates of LC, LRC, DFS, and OS were 87, 73, 63, and 83%, respectively. Angiosarcomas were found to be associated with worse LC, LRC, DFS, and OS. Patients over the age of 60 had lower rates of DFS. HNSTSs comprise a diverse group of tumors that can be managed with various treatment regimens involving RT. Angiosarcomas have higher recurrence and mortality rates.http://www.pagepress.org/journals/index.php/rt/article/view/6165AngiosarcomaHead and neck sarcomaRadiation therapyRadiotherapySoft tissue sarcoma |
| spellingShingle | Lucas K. Vitzthum Lindsay B. Brown Jessica W. Rooney Robert L. Foote Head and neck soft tissue sarcomas treated with radiation therapy Rare Tumors Angiosarcoma Head and neck sarcoma Radiation therapy Radiotherapy Soft tissue sarcoma |
| title | Head and neck soft tissue sarcomas treated with radiation therapy |
| title_full | Head and neck soft tissue sarcomas treated with radiation therapy |
| title_fullStr | Head and neck soft tissue sarcomas treated with radiation therapy |
| title_full_unstemmed | Head and neck soft tissue sarcomas treated with radiation therapy |
| title_short | Head and neck soft tissue sarcomas treated with radiation therapy |
| title_sort | head and neck soft tissue sarcomas treated with radiation therapy |
| topic | Angiosarcoma Head and neck sarcoma Radiation therapy Radiotherapy Soft tissue sarcoma |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/6165 |
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