CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway.

CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway.

Identification of stem cell-like brain tumor cells (brain tumor stem-like cells; BTSC) has gained substantial attention by scientists and physicians. However, the mechanism of tumor initiation and proliferation is still poorly understood. CD44 is a cell surface protein linked to tumorigenesis in var...

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Bibliographic Details
Main Authors: Mayumi Jijiwa, Habibe Demir, Snehalata Gupta, Crystal Leung, Kaushal Joshi, Nicholas Orozco, Tiffany Huang, Vedat O Yildiz, Ichiyo Shibahara, Jason A de Jesus, William H Yong, Paul S Mischel, Soledad Fernandez, Harley I Kornblum, Ichiro Nakano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3167830?pdf=render

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