Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance

Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance

Abstract Background Abundant reports indicated that depression was often comorbid with type 2 diabetes and even metabolic syndrome. Considering they might share common biological origins, it was tentatively attributed to the chronic cytokine-mediated inflammatory response which was induced by dysreg...

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Bibliographic Details
Main Authors: Wen-Jun Su, Wei Peng, Hong Gong, Yun-Zi Liu, Yi Zhang, Yong-Jie Lian, Zhi-Yong Cao, Ran Wu, Lin-Lin Liu, Bo Wang, Yun-Xia Wang, Chun-Lei Jiang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Neuroinflammation
Subjects:
Depression
Insulin resistance
Glyburide
NLRP3 inflammasome
Stress
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-017-0985-4

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