Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio

In current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full revers...

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Main Authors: Michael S. Kain, David Saper, Kyle Lybrand, Kasey-Jean Bramlett, Paul Tornetta III, Peter Althausen, John S. Garfi, Donald P. Willier III, Ruijia Niu, Andrew J. Marcantonio
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Geriatrics
Subjects:
Online Access:https://www.mdpi.com/2308-3417/5/3/43
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author Michael S. Kain
David Saper
Kyle Lybrand
Kasey-Jean Bramlett
Paul Tornetta III
Peter Althausen
John S. Garfi
Donald P. Willier III
Ruijia Niu
Andrew J. Marcantonio
author_facet Michael S. Kain
David Saper
Kyle Lybrand
Kasey-Jean Bramlett
Paul Tornetta III
Peter Althausen
John S. Garfi
Donald P. Willier III
Ruijia Niu
Andrew J. Marcantonio
author_sort Michael S. Kain
collection DOAJ
description In current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full reversal protocols may not be necessary, especially for patients with prior thromboembolic history. Our study aims to compare the surgical outcomes of patients with normal versus elevated INR values. We conducted a retrospective chart review on 217 patients who underwent surgeries on hip fractures at two academic trauma centers. We found that in our group (n = 124) of patients with an INR value of 1.5–3.0, there was only one reoperation for a hematoma, but there was a trend for more blood transfusions. There was no statistically significant difference in the odds of reoperation or overall complications. Nevertheless, there were significantly more events of postoperative anemia in this high INR patient group.
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spelling doaj.art-021f76fb41c742f296ab02d2e523603e2023-11-20T06:48:07ZengMDPI AGGeriatrics2308-34172020-07-01534310.3390/geriatrics5030043Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized RatioMichael S. Kain0David Saper1Kyle Lybrand2Kasey-Jean Bramlett3Paul Tornetta III4Peter Althausen5John S. Garfi6Donald P. Willier III7Ruijia Niu8Andrew J. Marcantonio9Department of Orthopaedic Surgery, Boston Medical Center, 850 Harrison Avenue, Boston, MA 02118, USAOrthopaedic and Rehabilitation Centers, 5616 North Western Avenue, Chicago, IL 60659, USAOrtho Montana, 2900 12th Avenue North, Billings, MT 59101, USADepartment of Orthopaedic Surgery, Lahey Hospital & Medical Center, 41 Mall Road, Burlington, MA 01805, USADepartment of Orthopaedic Surgery, Boston Medical Center, 850 Harrison Avenue, Boston, MA 02118, USAReno Orthopaedic Clinic, Reno, NV 89503, USADepartment of Orthopaedic Surgery, Lahey Hospital & Medical Center, 41 Mall Road, Burlington, MA 01805, USADepartment of Orthopaedic Surgery, Lahey Hospital & Medical Center, 41 Mall Road, Burlington, MA 01805, USADepartment of Orthopaedic Surgery, Boston Medical Center, 850 Harrison Avenue, Boston, MA 02118, USADepartment of Orthopaedic Surgery, Lahey Hospital & Medical Center, 41 Mall Road, Burlington, MA 01805, USAIn current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full reversal protocols may not be necessary, especially for patients with prior thromboembolic history. Our study aims to compare the surgical outcomes of patients with normal versus elevated INR values. We conducted a retrospective chart review on 217 patients who underwent surgeries on hip fractures at two academic trauma centers. We found that in our group (n = 124) of patients with an INR value of 1.5–3.0, there was only one reoperation for a hematoma, but there was a trend for more blood transfusions. There was no statistically significant difference in the odds of reoperation or overall complications. Nevertheless, there were significantly more events of postoperative anemia in this high INR patient group.https://www.mdpi.com/2308-3417/5/3/43hip fractureINRanticoagulationpostoperative complications
spellingShingle Michael S. Kain
David Saper
Kyle Lybrand
Kasey-Jean Bramlett
Paul Tornetta III
Peter Althausen
John S. Garfi
Donald P. Willier III
Ruijia Niu
Andrew J. Marcantonio
Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
Geriatrics
hip fracture
INR
anticoagulation
postoperative complications
title Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_full Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_fullStr Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_full_unstemmed Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_short Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_sort postoperative complications of hip fractures patients on chronic coumadin a comparison based on operative international normalized ratio
topic hip fracture
INR
anticoagulation
postoperative complications
url https://www.mdpi.com/2308-3417/5/3/43
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