SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome

SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome

Here we show that surface-enhanced Raman scattering (SERS) analysis captures the relative hypomethylation of DNA from patients with acute leukemia associated with Down syndrome (AL-DS) compared with patients diagnosed with transient leukemia associated with Down syndrome (TL-DS), an information infe...

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Bibliographic Details
Main Authors: Vlad Moisoiu, Valentina Sas, Andrei Stefancu, Stefania D. Iancu, Ancuta Jurj, Sergiu Pasca, Sabina Iluta, Alina-Andreea Zimta, Adrian B. Tigu, Patric Teodorescu, Cristina Turcas, Cristina Blag, Delia Dima, Gheorghe Popa, Smaranda Arghirescu, Sorin Man, Anca Colita, Nicolae Leopold, Ciprian Tomuleasa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
SERS
down syndrome
acute leukemia
transient leukemia associated with down syndrome
myeloproliferative neoplasm
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.703268/full

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