Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
Hyperpolarized metabolic contrast agents for magnetic resonance imaging can provide non-invasive and realtime information on tissue specific aberrant metabolism, but producing and handling them is highly demanding because of their short lifetime. Here a solid sample extraction, storage, and transpor...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2021-06-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-021-00536-9 |
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author | Andrea Capozzi Jan Kilund Magnus Karlsson Saket Patel Arthur Cesar Pinon François Vibert Olivier Ouari Mathilde H. Lerche Jan Henrik Ardenkjær-Larsen |
author_facet | Andrea Capozzi Jan Kilund Magnus Karlsson Saket Patel Arthur Cesar Pinon François Vibert Olivier Ouari Mathilde H. Lerche Jan Henrik Ardenkjær-Larsen |
author_sort | Andrea Capozzi |
collection | DOAJ |
description | Hyperpolarized metabolic contrast agents for magnetic resonance imaging can provide non-invasive and realtime information on tissue specific aberrant metabolism, but producing and handling them is highly demanding because of their short lifetime. Here a solid sample extraction, storage, and transport technique allows disconnecting production from end-user sites handling, as well as hour-long lifetimes of the agents. |
first_indexed | 2024-12-14T08:17:56Z |
format | Article |
id | doaj.art-02205f4eb13a4a5196a0a6fb9e88e441 |
institution | Directory Open Access Journal |
issn | 2399-3669 |
language | English |
last_indexed | 2024-12-14T08:17:56Z |
publishDate | 2021-06-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Communications Chemistry |
spelling | doaj.art-02205f4eb13a4a5196a0a6fb9e88e4412022-12-21T23:09:52ZengNature PortfolioCommunications Chemistry2399-36692021-06-014111110.1038/s42004-021-00536-9Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarizationAndrea Capozzi0Jan Kilund1Magnus Karlsson2Saket Patel3Arthur Cesar Pinon4François Vibert5Olivier Ouari6Mathilde H. Lerche7Jan Henrik Ardenkjær-Larsen8LIFMET, Department of Physics, EPFL, Station 6 (Batiment CH)HYPERMAG, Department of Health Technology, Technical University of DenmarkHYPERMAG, Department of Health Technology, Technical University of DenmarkHYPERMAG, Department of Health Technology, Technical University of DenmarkHYPERMAG, Department of Health Technology, Technical University of DenmarkInstitut de Chimie Radicalire Aix-Marseille Université, CNRS, ICR UMR 7273Institut de Chimie Radicalire Aix-Marseille Université, CNRS, ICR UMR 7273HYPERMAG, Department of Health Technology, Technical University of DenmarkHYPERMAG, Department of Health Technology, Technical University of DenmarkHyperpolarized metabolic contrast agents for magnetic resonance imaging can provide non-invasive and realtime information on tissue specific aberrant metabolism, but producing and handling them is highly demanding because of their short lifetime. Here a solid sample extraction, storage, and transport technique allows disconnecting production from end-user sites handling, as well as hour-long lifetimes of the agents.https://doi.org/10.1038/s42004-021-00536-9 |
spellingShingle | Andrea Capozzi Jan Kilund Magnus Karlsson Saket Patel Arthur Cesar Pinon François Vibert Olivier Ouari Mathilde H. Lerche Jan Henrik Ardenkjær-Larsen Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization Communications Chemistry |
title | Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization |
title_full | Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization |
title_fullStr | Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization |
title_full_unstemmed | Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization |
title_short | Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization |
title_sort | metabolic contrast agents produced from transported solid 13c glucose hyperpolarized via dynamic nuclear polarization |
url | https://doi.org/10.1038/s42004-021-00536-9 |
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