Epigenome‐Wide Association Study for All‐Cause Mortality in a Cardiovascular Cohort Identifies Differential Methylation in Castor Zinc Finger 1 (CASZ1)

Epigenome‐Wide Association Study for All‐Cause Mortality in a Cardiovascular Cohort Identifies Differential Methylation in Castor Zinc Finger 1 (CASZ1)

Background DNA methylation is implicated in many chronic diseases and may contribute to mortality. Therefore, we conducted an epigenome‐wide association study (EWAS) for all‐cause mortality with whole‐transcriptome data in a cardiovascular cohort (CATHGEN [Catheterization Genetics]). Methods and Res...

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Bibliographic Details
Main Authors: Jawan W. Abdulrahim, Lydia Coulter Kwee, Elizabeth Grass, Ilene C. Siegler, Redford Williams, Ravi Karra, William E. Kraus, Simon G. Gregory, Svati H. Shah
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac biomarkers
epigenetics
mortality
outcome
transcriptome
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.013228

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