Parenteral Vaccination with a Live <i>Brucella melitensis</i> Mutant Protects against Wild-Type <i>B. melitensis</i> 16M Challenge

Parenteral Vaccination with a Live <i>Brucella melitensis</i> Mutant Protects against Wild-Type <i>B. melitensis</i> 16M Challenge

Susceptibility to brucellosis remains prevalent, even in herds vaccinated with conventional vaccines. Efforts are underway to develop an improved brucellosis vaccine, and possibly a universal vaccine, given that <i>Brucella</i> species are highly homologous. To this end, two <i>B....

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Bibliographic Details
Main Authors: Xinghong Yang, Zakia I. Goodwin, Ella Bhagyaraj, Carol Hoffman, David W. Pascual
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Microorganisms
Subjects:
<i>Brucella</i>
T cells
IFN-γ
TNF-α
vaccine
Online Access:https://www.mdpi.com/2076-2607/12/1/169

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