PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?

Currently, hyperprolactinemia is considered as a condition to be excluded during the diagnosis of polycystic ovarian syndrome (PCOS), because it often demonstrates clinical signs similar to PCOS. However, some publications have reported “the prevalence of hyperprolactinemia in PCOS,” which does not...

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Main Authors: Alina V. Atalyan, Eldar M. Sharifulin, Lyudmila M. Lazareva, Yana G. Nadelyaeva, Larisa V. Suturina
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2021-12-01
Series:International Journal of Biomedicine
Subjects:
Online Access:http://ijbm.org/articles/i44/ijbm_11(4)_br1.pdf
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author Alina V. Atalyan
Eldar M. Sharifulin
Lyudmila M. Lazareva
Yana G. Nadelyaeva
Larisa V. Suturina
author_facet Alina V. Atalyan
Eldar M. Sharifulin
Lyudmila M. Lazareva
Yana G. Nadelyaeva
Larisa V. Suturina
author_sort Alina V. Atalyan
collection DOAJ
description Currently, hyperprolactinemia is considered as a condition to be excluded during the diagnosis of polycystic ovarian syndrome (PCOS), because it often demonstrates clinical signs similar to PCOS. However, some publications have reported “the prevalence of hyperprolactinemia in PCOS,” which does not agree with the statement above statement. The publications presented in this review demonstrate conflicting approaches to considering the association of hyperprolactinemia and PCOS. On the one hand, the current consensus on the diagnosis of PCOS assumes the exclusion of patients with hyperprolactinemia, and on the other hand, some authors consider hyperprolactinemia as an acceptable condition and estimate its prevalence in PCOS. Based on the analysis of the literature, we have demonstrated a contradictory attitude towards the association between hyperprolactinemia and PCOS. To overcome the contradiction, we consider it appropriate to use the term "potential PCOS" before the final assessment of the contribution of hyperprolactinemia to the development of symptoms similar to PCOS. The final diagnosis of PCOS in the presence of hyperprolactinemia is possible only after its correction and reassessment of all symptoms.
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spelling doaj.art-0221e55ad80f4786b783bb13dc0d8cae2022-12-21T19:23:17ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292021-12-0111448048310.21103/Article11(4)_BR1PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?Alina V. Atalyan0Eldar M. Sharifulin1Lyudmila M. Lazareva2Yana G. Nadelyaeva3Larisa V. Suturina4Scientific Centre for Family Health and Human Reproduction Problems, Irkutsk, the Russian FederationScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, the Russian FederationScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, the Russian FederationScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, the Russian FederationScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, the Russian FederationCurrently, hyperprolactinemia is considered as a condition to be excluded during the diagnosis of polycystic ovarian syndrome (PCOS), because it often demonstrates clinical signs similar to PCOS. However, some publications have reported “the prevalence of hyperprolactinemia in PCOS,” which does not agree with the statement above statement. The publications presented in this review demonstrate conflicting approaches to considering the association of hyperprolactinemia and PCOS. On the one hand, the current consensus on the diagnosis of PCOS assumes the exclusion of patients with hyperprolactinemia, and on the other hand, some authors consider hyperprolactinemia as an acceptable condition and estimate its prevalence in PCOS. Based on the analysis of the literature, we have demonstrated a contradictory attitude towards the association between hyperprolactinemia and PCOS. To overcome the contradiction, we consider it appropriate to use the term "potential PCOS" before the final assessment of the contribution of hyperprolactinemia to the development of symptoms similar to PCOS. The final diagnosis of PCOS in the presence of hyperprolactinemia is possible only after its correction and reassessment of all symptoms.http://ijbm.org/articles/i44/ijbm_11(4)_br1.pdfmacroprolactinemiapolycystic ovarian syndromehyperandrogenismhirsutism
spellingShingle Alina V. Atalyan
Eldar M. Sharifulin
Lyudmila M. Lazareva
Yana G. Nadelyaeva
Larisa V. Suturina
PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?
International Journal of Biomedicine
macroprolactinemia
polycystic ovarian syndrome
hyperandrogenism
hirsutism
title PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?
title_full PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?
title_fullStr PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?
title_full_unstemmed PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?
title_short PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?
title_sort pcos and hyperprolactinemia conflicting conditions or comorbidities
topic macroprolactinemia
polycystic ovarian syndrome
hyperandrogenism
hirsutism
url http://ijbm.org/articles/i44/ijbm_11(4)_br1.pdf
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AT eldarmsharifulin pcosandhyperprolactinemiaconflictingconditionsorcomorbidities
AT lyudmilamlazareva pcosandhyperprolactinemiaconflictingconditionsorcomorbidities
AT yanagnadelyaeva pcosandhyperprolactinemiaconflictingconditionsorcomorbidities
AT larisavsuturina pcosandhyperprolactinemiaconflictingconditionsorcomorbidities