In vitro assessment of the anthelmintic activity of copper oxide and zinc oxide nanoparticles on egg and adult stages of Fasciola hepatica: evidence on oxidative stress biomarkers, and DNA damage

In vitro assessment of the anthelmintic activity of copper oxide and zinc oxide nanoparticles on egg and adult stages of Fasciola hepatica: evidence on oxidative stress biomarkers, and DNA damage

Abstract Objectives Fasciolosis is of significant economic and public health importance worldwide. The lack of a successful vaccine and emerging resistance in flukes to the drug of choice, triclabendazole, has initiated the search for alternative approaches. In recent years, metallic nanoparticles h...

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Bibliographic Details
Main Authors: Amirhassan Ravvaz, Farnaz Malekifard, Bijan Esmaeilnejad
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Veterinary Research
Subjects:
Copper oxide nanoparticles
DNA damage
Fasciola hepatica
In vitro
Anthelmintic activity
Oxidative stress
Online Access:https://doi.org/10.1186/s12917-024-03994-0

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