Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care
Abstract Background Hyperactive delirium is known to increase family distress and the burden on health care providers. We compared the prevalence and associated factors of agitated delirium in advanced cancer patients between inpatient palliative care and palliative home care on admission and at 3 d...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-02-01
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| Series: | Cancer Medicine |
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| Online Access: | https://doi.org/10.1002/cam4.3661 |
| _version_ | 1819169406006067200 |
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| author | Jun Hamano Masanori Mori Taketoshi Ozawa Jun Sasaki Masanori Kawahara Asumi Nakamura Kotaro Hashimoto Kazuhiro Hisajima Tomoyuki Koga Keiji Goto Kazuhiko Fukumoto Yuri Morimoto Masahiro Goshima Go Sekimoto Mika Baba Kiyofumi Oya Ryo Matsunuma Yukari Azuma Kengo Imai Tatsuya Morita Takuya Shinjo |
| author_facet | Jun Hamano Masanori Mori Taketoshi Ozawa Jun Sasaki Masanori Kawahara Asumi Nakamura Kotaro Hashimoto Kazuhiro Hisajima Tomoyuki Koga Keiji Goto Kazuhiko Fukumoto Yuri Morimoto Masahiro Goshima Go Sekimoto Mika Baba Kiyofumi Oya Ryo Matsunuma Yukari Azuma Kengo Imai Tatsuya Morita Takuya Shinjo |
| author_sort | Jun Hamano |
| collection | DOAJ |
| description | Abstract Background Hyperactive delirium is known to increase family distress and the burden on health care providers. We compared the prevalence and associated factors of agitated delirium in advanced cancer patients between inpatient palliative care and palliative home care on admission and at 3 days before death. Methods This was a post hoc exploratory analysis of two multicenter, prospective cohort studies of advanced cancer patients, which were performed at 23 palliative care units (PCUs) between Jan and Dec 2017, and on 45 palliative home care services between July and Dec 2017. Results In total, 2998 patients were enrolled and 2829 were analyzed in this study: 1883 patients in PCUs and 947 patients in palliative home care. The prevalence of agitated delirium between PCUs and palliative home care was 5.2% (95% CI: 4.2% ‐ 6.3%) vs. 1.4% (0.7% ‐ 2.3%) on admission (p < 0.001) and 7.6% (6.4% ‐ 8.9%) vs. 5.4% (4.0% ‐ 7.0%) 3 days before death (p < 0.001). However, multivariate logistic regression analysis revealed that the place of care was not significantly associated with the prevalence of agitated delirium at 3 days before death after adjusting for prognostic factors, physical risk factors, and symptoms. Conclusions There was no significant difference in the prevalence of agitated delirium at 3 days before death between inpatient palliative care and palliative home care after adjusting for the patient background, prognostic factors, symptoms, and treatment. |
| first_indexed | 2024-12-22T19:18:59Z |
| format | Article |
| id | doaj.art-022440ad25584b728d839c01e9f0e08f |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-12-22T19:18:59Z |
| publishDate | 2021-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-022440ad25584b728d839c01e9f0e08f2022-12-21T18:15:25ZengWileyCancer Medicine2045-76342021-02-011031166117910.1002/cam4.3661Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home careJun Hamano0Masanori Mori1Taketoshi Ozawa2Jun Sasaki3Masanori Kawahara4Asumi Nakamura5Kotaro Hashimoto6Kazuhiro Hisajima7Tomoyuki Koga8Keiji Goto9Kazuhiko Fukumoto10Yuri Morimoto11Masahiro Goshima12Go Sekimoto13Mika Baba14Kiyofumi Oya15Ryo Matsunuma16Yukari Azuma17Kengo Imai18Tatsuya Morita19Takuya Shinjo20Division of Clinical Medicine Faculty of Medicine University of Tsukuba Tsukuba JapanSeirei Mikatahara General Hospital Shizuoka JapanMegumi Zaitaku Clinic Yokohama JapanYushoukai Medical Corporation Tokyo JapanSoshukai Okabe Clinic Sendai Miyagi JapanHimawari Clinic Chiba JapanFukushima Home Palliative Care Clinic Fukushima JapanDr. GON Kamakura Clinic Kanagawa JapanNozominohana Clinic Chiba JapanHimawari clinic Kumamoto JapanIwata Home Care Clinic Shizuoka JapanMorimoto Clinic Hyogo JapanHome care clinic Kobe Hyofo JapanSekimoto Clinic Hyogo JapanDepartment of Palliative Medicine Suita Tokushukai Hospital Suita JapanDepartment of Palliative and Supportive Care Aso Iizuka Hospital Fukuoka JapanDepartment of Palliative Medicine Kobe University Graduate school of Medicine Hyogo JapanTokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Tokyo JapanSeirei HospiceSeirei Mikatahara General Hospital Shizuoka JapanDepartment of Palliative and Supportive Care Palliative Care Team, and Seirei HospiceSeirei Mikatahara General Hospital Shizuoka JapanShinjo‐clinic Hyogo JapanAbstract Background Hyperactive delirium is known to increase family distress and the burden on health care providers. We compared the prevalence and associated factors of agitated delirium in advanced cancer patients between inpatient palliative care and palliative home care on admission and at 3 days before death. Methods This was a post hoc exploratory analysis of two multicenter, prospective cohort studies of advanced cancer patients, which were performed at 23 palliative care units (PCUs) between Jan and Dec 2017, and on 45 palliative home care services between July and Dec 2017. Results In total, 2998 patients were enrolled and 2829 were analyzed in this study: 1883 patients in PCUs and 947 patients in palliative home care. The prevalence of agitated delirium between PCUs and palliative home care was 5.2% (95% CI: 4.2% ‐ 6.3%) vs. 1.4% (0.7% ‐ 2.3%) on admission (p < 0.001) and 7.6% (6.4% ‐ 8.9%) vs. 5.4% (4.0% ‐ 7.0%) 3 days before death (p < 0.001). However, multivariate logistic regression analysis revealed that the place of care was not significantly associated with the prevalence of agitated delirium at 3 days before death after adjusting for prognostic factors, physical risk factors, and symptoms. Conclusions There was no significant difference in the prevalence of agitated delirium at 3 days before death between inpatient palliative care and palliative home care after adjusting for the patient background, prognostic factors, symptoms, and treatment.https://doi.org/10.1002/cam4.3661advanced cancer patientshyperactive deliriuminpatient palliative carepalliative home careplace of care |
| spellingShingle | Jun Hamano Masanori Mori Taketoshi Ozawa Jun Sasaki Masanori Kawahara Asumi Nakamura Kotaro Hashimoto Kazuhiro Hisajima Tomoyuki Koga Keiji Goto Kazuhiko Fukumoto Yuri Morimoto Masahiro Goshima Go Sekimoto Mika Baba Kiyofumi Oya Ryo Matsunuma Yukari Azuma Kengo Imai Tatsuya Morita Takuya Shinjo Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care Cancer Medicine advanced cancer patients hyperactive delirium inpatient palliative care palliative home care place of care |
| title | Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care |
| title_full | Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care |
| title_fullStr | Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care |
| title_full_unstemmed | Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care |
| title_short | Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care |
| title_sort | comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care |
| topic | advanced cancer patients hyperactive delirium inpatient palliative care palliative home care place of care |
| url | https://doi.org/10.1002/cam4.3661 |
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