Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction?
<p>Abstract</p> <p>Neurocognitive disorders are emerging as a possible complication in patients infected with HIV. Even if asymptomatic, neurocognitive abnormalities are frequently detected using a battery of tests. This supported the creation of asymptomatic neurocognitive impairm...
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| Format: | Article |
| Language: | English |
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BMC
2011-12-01
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| Series: | BMC Medicine |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1741-7015/9/138 |
| _version_ | 1831768217522012160 |
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| author | Torti Carlo Focà Emanuele Cesana Bruno M Lescure Francois X |
| author_facet | Torti Carlo Focà Emanuele Cesana Bruno M Lescure Francois X |
| author_sort | Torti Carlo |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Neurocognitive disorders are emerging as a possible complication in patients infected with HIV. Even if asymptomatic, neurocognitive abnormalities are frequently detected using a battery of tests. This supported the creation of asymptomatic neurocognitive impairment (ANI) as a new entity. In a recent article published in BMC Infectious Diseases, Magnus Gisslén and colleagues applied a statistical approach, concluding that there is an overestimation of the actual problem. In fact, about 20% of patients are classified as neurocognitively impaired without a clear impact on daily activities. In the present commentary, we discuss the clinical implications of their findings. Although a cautious approach would indicate a stricter follow-up of patients affected by this disorder, it is premature to consider it as a proper disease. Based on a review of the data in the current literature we conclude that it is urgent to conduct more studies to estimate the overall risk of progression of the asymptomatic neurocognitive impairment. Moreover, it is important to understand whether new biomarkers or neuroimaging tools can help to identify better the most at risk population.</p> <p>Please see related article: <url>http://www.biomedcentral.com/1471-2334/11/356</url></p> |
| first_indexed | 2024-12-22T06:56:45Z |
| format | Article |
| id | doaj.art-022730a049b84b89b8c2a71f7f69f6df |
| institution | Directory Open Access Journal |
| issn | 1741-7015 |
| language | English |
| last_indexed | 2024-12-22T06:56:45Z |
| publishDate | 2011-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medicine |
| spelling | doaj.art-022730a049b84b89b8c2a71f7f69f6df2022-12-21T18:34:54ZengBMCBMC Medicine1741-70152011-12-019113810.1186/1741-7015-9-138Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction?Torti CarloFocà EmanueleCesana Bruno MLescure Francois X<p>Abstract</p> <p>Neurocognitive disorders are emerging as a possible complication in patients infected with HIV. Even if asymptomatic, neurocognitive abnormalities are frequently detected using a battery of tests. This supported the creation of asymptomatic neurocognitive impairment (ANI) as a new entity. In a recent article published in BMC Infectious Diseases, Magnus Gisslén and colleagues applied a statistical approach, concluding that there is an overestimation of the actual problem. In fact, about 20% of patients are classified as neurocognitively impaired without a clear impact on daily activities. In the present commentary, we discuss the clinical implications of their findings. Although a cautious approach would indicate a stricter follow-up of patients affected by this disorder, it is premature to consider it as a proper disease. Based on a review of the data in the current literature we conclude that it is urgent to conduct more studies to estimate the overall risk of progression of the asymptomatic neurocognitive impairment. Moreover, it is important to understand whether new biomarkers or neuroimaging tools can help to identify better the most at risk population.</p> <p>Please see related article: <url>http://www.biomedcentral.com/1471-2334/11/356</url></p>http://www.biomedcentral.com/1741-7015/9/138HIVasymptomatic neurocognitive impairmentHIV dementiaHAART |
| spellingShingle | Torti Carlo Focà Emanuele Cesana Bruno M Lescure Francois X Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction? BMC Medicine HIV asymptomatic neurocognitive impairment HIV dementia HAART |
| title | Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction? |
| title_full | Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction? |
| title_fullStr | Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction? |
| title_full_unstemmed | Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction? |
| title_short | Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction? |
| title_sort | asymptomatic neurocognitive disorders in patients infected by hiv fact or fiction |
| topic | HIV asymptomatic neurocognitive impairment HIV dementia HAART |
| url | http://www.biomedcentral.com/1741-7015/9/138 |
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