Mammalian target of rapamycin inhibition in polycystic kidney disease: From bench to bedside
Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening hereditary disease in the USA resulting in chronic kidney disease and the need for dialysis and transplantation. Approximately 85% of cases of ADPKD are caused by a mutation in the Pkd1 gene that encodes polycys...
Main Authors: | Hyun-Jung Kim, Charles L. Edelstein |
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Nephrology
2012-09-01
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Series: | Kidney Research and Clinical Practice |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913212007115 |
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