Acetate rescues defective brain-adipose metabolic network in obese Wistar rats by modulation of peroxisome proliferator-activated receptor-γ

Abstract We investigated the hypothesis that acetate ameliorates brain-adipose metabolic dysfunction (BAMED) in high fat diet (HFD)-induced obesity, possibly by modulation of peroxisome proliferator-activated receptor-γ (PPAR-γ). Ten-week-old male Wistar rats were randomly assigned into four groups...

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Bibliographic Details
Main Authors: Kehinde Samuel Olaniyi, Morounkeji Nicole Owolabi, Chukwubueze Lucky Atuma, Toluwani Bosede Agunbiade, Bolanle Yemisi Alabi
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98605-5