Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report
Abstract Malignant gastrointestinal neuroectodermal tumors (GNETs) are rare malignant mesenchymal neoplasms. To our knowledge, only 99 cases have been reported worldwide. The tumor has an aggressive malignancy, with a rapid progression. The histological features of GNET overlap with those of clear c...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-04-01
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| Series: | DEN Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/deo2.119 |
| _version_ | 1811312397502119936 |
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| author | Makiko Sasaki Mamoru Tanaka Koki Asukai Hiroki Koguchi Yusuke Inoue Mizuki Moriyama Tetsuo Tsukahara Takeo Kawahara Eiji Hayashi Yukinori Hattori Izumi Hasegawa Hiromi Kataoka |
| author_facet | Makiko Sasaki Mamoru Tanaka Koki Asukai Hiroki Koguchi Yusuke Inoue Mizuki Moriyama Tetsuo Tsukahara Takeo Kawahara Eiji Hayashi Yukinori Hattori Izumi Hasegawa Hiromi Kataoka |
| author_sort | Makiko Sasaki |
| collection | DOAJ |
| description | Abstract Malignant gastrointestinal neuroectodermal tumors (GNETs) are rare malignant mesenchymal neoplasms. To our knowledge, only 99 cases have been reported worldwide. The tumor has an aggressive malignancy, with a rapid progression. The histological features of GNET overlap with those of clear cell sarcoma, which contain Ewing sarcoma breakpoint region 1 mutation. GNETs lack melanocyte‐specific markers, while clear cell sarcoma exhibits melanocytic differentiation. Various symptoms have been reported previously, and the most reported lesion is in the small bowel. The patient was a 69‐year‐old man who presented with abdominal pain and vomiting. Computed tomography revealed a nodule in the small bowel, which induced small intestinal obstruction. Enteroscopic images revealed a submucosal tumor. Surgery was performed, and the patient was diagnosed with GNET. Only two patients whose primary lesions were in the small intestine, including the patient in this report, have undergone enteroscopy before surgery. This is a rare case of GNET in which a patient underwent enteroscopy before surgical treatment. |
| first_indexed | 2024-04-13T10:36:37Z |
| format | Article |
| id | doaj.art-022862490d184820a3436e7a8267bc1d |
| institution | Directory Open Access Journal |
| issn | 2692-4609 |
| language | English |
| last_indexed | 2024-04-13T10:36:37Z |
| publishDate | 2022-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj.art-022862490d184820a3436e7a8267bc1d2022-12-22T02:50:03ZengWileyDEN Open2692-46092022-04-0121n/an/a10.1002/deo2.119Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case reportMakiko Sasaki0Mamoru Tanaka1Koki Asukai2Hiroki Koguchi3Yusuke Inoue4Mizuki Moriyama5Tetsuo Tsukahara6Takeo Kawahara7Eiji Hayashi8Yukinori Hattori9Izumi Hasegawa10Hiromi Kataoka11Department of Gastroenterology Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Science Aichi JapanDepartment of Gastroenterology Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Gastroenterology Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Gastroenterology Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Surgery Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Surgery Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Surgery Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Surgery Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Pathology Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Gastroenterology Japan Community Health Care Organization Chukyo Hospital Aichi JapanDepartment of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Science Aichi JapanAbstract Malignant gastrointestinal neuroectodermal tumors (GNETs) are rare malignant mesenchymal neoplasms. To our knowledge, only 99 cases have been reported worldwide. The tumor has an aggressive malignancy, with a rapid progression. The histological features of GNET overlap with those of clear cell sarcoma, which contain Ewing sarcoma breakpoint region 1 mutation. GNETs lack melanocyte‐specific markers, while clear cell sarcoma exhibits melanocytic differentiation. Various symptoms have been reported previously, and the most reported lesion is in the small bowel. The patient was a 69‐year‐old man who presented with abdominal pain and vomiting. Computed tomography revealed a nodule in the small bowel, which induced small intestinal obstruction. Enteroscopic images revealed a submucosal tumor. Surgery was performed, and the patient was diagnosed with GNET. Only two patients whose primary lesions were in the small intestine, including the patient in this report, have undergone enteroscopy before surgery. This is a rare case of GNET in which a patient underwent enteroscopy before surgical treatment.https://doi.org/10.1002/deo2.119balloon enteroscopyclear cell sarcomaintestinal obstructionneuroectodermal tumorsmall intestine |
| spellingShingle | Makiko Sasaki Mamoru Tanaka Koki Asukai Hiroki Koguchi Yusuke Inoue Mizuki Moriyama Tetsuo Tsukahara Takeo Kawahara Eiji Hayashi Yukinori Hattori Izumi Hasegawa Hiromi Kataoka Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report DEN Open balloon enteroscopy clear cell sarcoma intestinal obstruction neuroectodermal tumor small intestine |
| title | Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report |
| title_full | Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report |
| title_fullStr | Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report |
| title_full_unstemmed | Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report |
| title_short | Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report |
| title_sort | malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction a case report |
| topic | balloon enteroscopy clear cell sarcoma intestinal obstruction neuroectodermal tumor small intestine |
| url | https://doi.org/10.1002/deo2.119 |
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