Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved]
For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful effects. The occurrence of contrast-associate...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2019-05-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-753/v1 |
| _version_ | 1828832292708024320 |
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| author | Wim Vandenberghe Eric Hoste |
| author_facet | Wim Vandenberghe Eric Hoste |
| author_sort | Wim Vandenberghe |
| collection | DOAJ |
| description | For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful effects. The occurrence of contrast-associated AKI was likely overestimated in the past because of confounders for AKI. Several strategies have been investigated to reduce contrast-associated AKI but even for the most important one, hydration, there are conflicting data. Even if the occurrence rate of contrast-associated AKI is low, AKI is related to worse outcomes. Therefore, besides limiting contrast agent usage, general AKI preventive measurements should be applied in at-risk patients. |
| first_indexed | 2024-12-12T16:51:16Z |
| format | Article |
| id | doaj.art-022a2fc4b93646fb9567d2a8a19f4222 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-12T16:51:16Z |
| publishDate | 2019-05-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-022a2fc4b93646fb9567d2a8a19f42222022-12-22T00:18:21ZengF1000 Research LtdF1000Research2046-14022019-05-01810.12688/f1000research.16347.117857Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved]Wim Vandenberghe0Eric Hoste1Department of Intensive Care Medicine, University Hospital Ghent, Ghent University, C. Heymanslaan 10, 9000 Ghent, BelgiumDepartment of Intensive Care Medicine, University Hospital Ghent, Ghent University, C. Heymanslaan 10, 9000 Ghent, BelgiumFor decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful effects. The occurrence of contrast-associated AKI was likely overestimated in the past because of confounders for AKI. Several strategies have been investigated to reduce contrast-associated AKI but even for the most important one, hydration, there are conflicting data. Even if the occurrence rate of contrast-associated AKI is low, AKI is related to worse outcomes. Therefore, besides limiting contrast agent usage, general AKI preventive measurements should be applied in at-risk patients.https://f1000research.com/articles/8-753/v1 |
| spellingShingle | Wim Vandenberghe Eric Hoste Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] F1000Research |
| title | Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] |
| title_full | Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] |
| title_fullStr | Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] |
| title_full_unstemmed | Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] |
| title_short | Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] |
| title_sort | contrast associated acute kidney injury does it really exist and if so what to do about it version 1 peer review 2 approved |
| url | https://f1000research.com/articles/8-753/v1 |
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