A Complete Response to Combined Immunotherapy in a Patient with an ATM plus SF3B1 Mutation and a Moderate Tumor Mutational Burden with a High-Grade Treatment-Emergent Neuroendocrine Prostate Cancer: Case Report and Review of the Literature

A Complete Response to Combined Immunotherapy in a Patient with an ATM plus SF3B1 Mutation and a Moderate Tumor Mutational Burden with a High-Grade Treatment-Emergent Neuroendocrine Prostate Cancer: Case Report and Review of the Literature

Introduction: High-grade treatment-emergent neuroendocrine prostate cancer (T-NEPC) is a rare subtype of prostate cancer with limited therapeutic options and poor prognosis. Understanding biomarkers that influence the efficacy of immune checkpoint inhibitors (IO) is vital to form a better therapeuti...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Helena Ferreira Bruzzi Porto, Gabriela C.K. Lopes, Hannah B.V. Bekierman, Sérgio Altino De Almeida, Felipe Da Matta Andreiuolo, Evandro Lucena, Sandip Pravin Patel, Vinicius Freire, Daniel Herchenhorn
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Karger Publishers 2024-08-01
Sraith:Case Reports in Oncology
Ábhair:
neuroendocrine carcinoma
prostate cancer
immunotherapy
Rochtain ar líne:https://beta.karger.com/Article/FullText/540573

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https://beta.karger.com/Article/FullText/540573

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