A Complete Response to Combined Immunotherapy in a Patient with an ATM plus SF3B1 Mutation and a Moderate Tumor Mutational Burden with a High-Grade Treatment-Emergent Neuroendocrine Prostate Cancer: Case Report and Review of the Literature

A Complete Response to Combined Immunotherapy in a Patient with an ATM plus SF3B1 Mutation and a Moderate Tumor Mutational Burden with a High-Grade Treatment-Emergent Neuroendocrine Prostate Cancer: Case Report and Review of the Literature

Introduction: High-grade treatment-emergent neuroendocrine prostate cancer (T-NEPC) is a rare subtype of prostate cancer with limited therapeutic options and poor prognosis. Understanding biomarkers that influence the efficacy of immune checkpoint inhibitors (IO) is vital to form a better therapeuti...

Full description

Bibliographic Details
Main Authors: Helena Ferreira Bruzzi Porto, Gabriela C.K. Lopes, Hannah B.V. Bekierman, Sérgio Altino De Almeida, Felipe Da Matta Andreiuolo, Evandro Lucena, Sandip Pravin Patel, Vinicius Freire, Daniel Herchenhorn
Format: Article
Language:English
Published: Karger Publishers 2024-08-01
Series:Case Reports in Oncology
Subjects:
neuroendocrine carcinoma
prostate cancer
immunotherapy
Online Access:https://beta.karger.com/Article/FullText/540573

Internet

https://beta.karger.com/Article/FullText/540573

Similar Items