Post-kala-azar dermal leishmaniasis associated with AIDS

Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature...

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Main Authors: Bittencourt Achiléa, Silva Nancy, Straatmann Andréa, Nunes Victor Luiz Correia, Follador Ivonise, Badaró Roberto
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600008
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author Bittencourt Achiléa
Silva Nancy
Straatmann Andréa
Nunes Victor Luiz Correia
Follador Ivonise
Badaró Roberto
author_facet Bittencourt Achiléa
Silva Nancy
Straatmann Andréa
Nunes Victor Luiz Correia
Follador Ivonise
Badaró Roberto
author_sort Bittencourt Achiléa
collection DOAJ
description Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a "saw-tooth" pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.
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spelling doaj.art-022fff1fa4e948258b7ff82d1f645b612022-12-21T23:57:44ZengElsevierBrazilian Journal of Infectious Diseases1413-86701678-43912002-01-0166313316Post-kala-azar dermal leishmaniasis associated with AIDSBittencourt AchiléaSilva NancyStraatmann AndréaNunes Victor Luiz CorreiaFollador IvoniseBadaró RobertoPost-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a "saw-tooth" pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600008Visceral leishmaniasispost-kala-azar dermal leishmaniasisAIDS
spellingShingle Bittencourt Achiléa
Silva Nancy
Straatmann Andréa
Nunes Victor Luiz Correia
Follador Ivonise
Badaró Roberto
Post-kala-azar dermal leishmaniasis associated with AIDS
Brazilian Journal of Infectious Diseases
Visceral leishmaniasis
post-kala-azar dermal leishmaniasis
AIDS
title Post-kala-azar dermal leishmaniasis associated with AIDS
title_full Post-kala-azar dermal leishmaniasis associated with AIDS
title_fullStr Post-kala-azar dermal leishmaniasis associated with AIDS
title_full_unstemmed Post-kala-azar dermal leishmaniasis associated with AIDS
title_short Post-kala-azar dermal leishmaniasis associated with AIDS
title_sort post kala azar dermal leishmaniasis associated with aids
topic Visceral leishmaniasis
post-kala-azar dermal leishmaniasis
AIDS
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600008
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