Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix
Primary squamous cell carcinoma or squamous intraepithelial lesion of the fallopian tube is a very rare finding with only a small number of cases worldwide. We describe the case of a 51-year-old woman, undergoing an abdominal hysterectomy after the diagnosis of an HPV-associated invasive squamous ce...
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| Format: | Article |
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MDPI AG
2023-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/17/2836 |
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| author | Anne-Sophie Wegscheider Nikolas Tauber Kirsten Graubner Gudrun Ziegeler Michael Behr Christoph Lindner Axel Niendorf |
| author_facet | Anne-Sophie Wegscheider Nikolas Tauber Kirsten Graubner Gudrun Ziegeler Michael Behr Christoph Lindner Axel Niendorf |
| author_sort | Anne-Sophie Wegscheider |
| collection | DOAJ |
| description | Primary squamous cell carcinoma or squamous intraepithelial lesion of the fallopian tube is a very rare finding with only a small number of cases worldwide. We describe the case of a 51-year-old woman, undergoing an abdominal hysterectomy after the diagnosis of an HPV-associated invasive squamous cell carcinoma of the uterine cervix with the unexpected detection of an HPV16-positive high-grade squamous intraepithelial lesion of the fimbria of the right fallopian tube in the resection specimen. The finding of an isolated, HPV-associated squamous intraepithelial lesion in the fallopian tube raises the question of a de novo development in this body compartment (after exclusion of a continuous metastatic spread from the uterine cervix) by taking a virus-associated field effect into account and should encourage the inclusion of this possibility when examining the fallopian tube in a routine setting. |
| first_indexed | 2024-03-10T23:25:16Z |
| format | Article |
| id | doaj.art-0230e5c5b63042848d600aa42dc6637c |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T23:25:16Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-0230e5c5b63042848d600aa42dc6637c2023-11-19T08:00:13ZengMDPI AGDiagnostics2075-44182023-09-011317283610.3390/diagnostics13172836Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine CervixAnne-Sophie Wegscheider0Nikolas Tauber1Kirsten Graubner2Gudrun Ziegeler3Michael Behr4Christoph Lindner5Axel Niendorf6MVZ Prof. Dr. Med. A. Niendorf Pathologie Hamburg-West GmbH, 22767 Hamburg, GermanyDepartment of Gynecology, Agaplesion Diakonieklinikum Hamburg, 20259 Hamburg, GermanyDepartment of Gynecology, Agaplesion Diakonieklinikum Hamburg, 20259 Hamburg, GermanyMVZ Prof. Dr. Med. A. Niendorf Pathologie Hamburg-West GmbH, 22767 Hamburg, GermanyMVZ Prof. Dr. Med. A. Niendorf Pathologie Hamburg-West GmbH, 22767 Hamburg, GermanyDepartment of Gynecology, Agaplesion Diakonieklinikum Hamburg, 20259 Hamburg, GermanyMVZ Prof. Dr. Med. A. Niendorf Pathologie Hamburg-West GmbH, 22767 Hamburg, GermanyPrimary squamous cell carcinoma or squamous intraepithelial lesion of the fallopian tube is a very rare finding with only a small number of cases worldwide. We describe the case of a 51-year-old woman, undergoing an abdominal hysterectomy after the diagnosis of an HPV-associated invasive squamous cell carcinoma of the uterine cervix with the unexpected detection of an HPV16-positive high-grade squamous intraepithelial lesion of the fimbria of the right fallopian tube in the resection specimen. The finding of an isolated, HPV-associated squamous intraepithelial lesion in the fallopian tube raises the question of a de novo development in this body compartment (after exclusion of a continuous metastatic spread from the uterine cervix) by taking a virus-associated field effect into account and should encourage the inclusion of this possibility when examining the fallopian tube in a routine setting.https://www.mdpi.com/2075-4418/13/17/2836fallopian tubefimbriaesquamous cell intraepithelial neoplasiasquamous cell carcinomacarcinoma of uterine cervixHPV |
| spellingShingle | Anne-Sophie Wegscheider Nikolas Tauber Kirsten Graubner Gudrun Ziegeler Michael Behr Christoph Lindner Axel Niendorf Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix Diagnostics fallopian tube fimbriae squamous cell intraepithelial neoplasia squamous cell carcinoma carcinoma of uterine cervix HPV |
| title | Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix |
| title_full | Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix |
| title_fullStr | Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix |
| title_full_unstemmed | Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix |
| title_short | Synchronous High-Grade Squamous Intraepithelial Lesion of the Fimbria of the Fallopian Tube in a 51-Year-Old Woman with Invasive Squamous Cell Carcinoma of the Uterine Cervix |
| title_sort | synchronous high grade squamous intraepithelial lesion of the fimbria of the fallopian tube in a 51 year old woman with invasive squamous cell carcinoma of the uterine cervix |
| topic | fallopian tube fimbriae squamous cell intraepithelial neoplasia squamous cell carcinoma carcinoma of uterine cervix HPV |
| url | https://www.mdpi.com/2075-4418/13/17/2836 |
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