Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage
Abstract The purpose of the present study was to fabricate a miniscrew possible for clinical application using Zr70Ni16Cu6Al8 bulk metallic glass (BMG), which has high mechanical strength, low elastic modulus, and high biocompatibility. First, the elastic moduli of Zr-based metallic glass rods made...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-30102-3 |
| _version_ | 1797864873880715264 |
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| author | Shutaro Sasaki Masahiro Seiryu Hiroto Ida Shunro Miyashita Nobuo Takeshita Daiki Irie Yoshihiko Yokoyama Teruko Takano-Yamamoto |
| author_facet | Shutaro Sasaki Masahiro Seiryu Hiroto Ida Shunro Miyashita Nobuo Takeshita Daiki Irie Yoshihiko Yokoyama Teruko Takano-Yamamoto |
| author_sort | Shutaro Sasaki |
| collection | DOAJ |
| description | Abstract The purpose of the present study was to fabricate a miniscrew possible for clinical application using Zr70Ni16Cu6Al8 bulk metallic glass (BMG), which has high mechanical strength, low elastic modulus, and high biocompatibility. First, the elastic moduli of Zr-based metallic glass rods made of Zr55Ni5Cu30Al10, Zr60Ni10Cu20Al10, Zr65Ni10Cu17.5Al7.5, Zr68Ni12Cu12Al8, and Zr70Ni16Cu6Al8 were measured. Zr70Ni16Cu6Al8 had the lowest elastic modulus among them. Then, we fabricated Zr70Ni16Cu6Al8 BMG miniscrews with diameters from 0.9 to 1.3 mm, conducted a torsion test, and implanted them into the alveolar bone of beagle dogs to compare insertion torque, removal torque, Periotest, new bone formation around the miniscrew, and failure rate compared with 1.3 mm diameter Ti-6Al-4 V miniscrew. The Zr70Ni16Cu6Al8 BMG miniscrew exhibited a high torsion torque even if the miniscrew had a small diameter. Zr70Ni16Cu6Al8 BMG miniscrews with a diameter of 1.1 mm or less had higher stability and lower failure rate than 1.3 mm diameter Ti-6Al-4 V miniscrews. Furthermore, the smaller diameter Zr70Ni16Cu6Al8 BMG miniscrew was shown, for the first time, to have a higher success rate and to form more new bone around the miniscrew. These findings suggested the usefulness of our novel small miniscrew made of Zr70Ni16Cu6Al8 BMG for orthodontic anchorage. |
| first_indexed | 2024-04-09T22:59:01Z |
| format | Article |
| id | doaj.art-0235710b5a8a44ffad2555eb02591a93 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T22:59:01Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-0235710b5a8a44ffad2555eb02591a932023-03-22T11:02:56ZengNature PortfolioScientific Reports2045-23222023-02-0113111310.1038/s41598-023-30102-3Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorageShutaro Sasaki0Masahiro Seiryu1Hiroto Ida2Shunro Miyashita3Nobuo Takeshita4Daiki Irie5Yoshihiko Yokoyama6Teruko Takano-Yamamoto7Division of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryDivision of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryDivision of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryDivision of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryDivision of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryDivision of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryCooperative Research and Development Center for Advanced Materials, Institute for Materials Research, Tohoku UniversityDivision of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of DentistryAbstract The purpose of the present study was to fabricate a miniscrew possible for clinical application using Zr70Ni16Cu6Al8 bulk metallic glass (BMG), which has high mechanical strength, low elastic modulus, and high biocompatibility. First, the elastic moduli of Zr-based metallic glass rods made of Zr55Ni5Cu30Al10, Zr60Ni10Cu20Al10, Zr65Ni10Cu17.5Al7.5, Zr68Ni12Cu12Al8, and Zr70Ni16Cu6Al8 were measured. Zr70Ni16Cu6Al8 had the lowest elastic modulus among them. Then, we fabricated Zr70Ni16Cu6Al8 BMG miniscrews with diameters from 0.9 to 1.3 mm, conducted a torsion test, and implanted them into the alveolar bone of beagle dogs to compare insertion torque, removal torque, Periotest, new bone formation around the miniscrew, and failure rate compared with 1.3 mm diameter Ti-6Al-4 V miniscrew. The Zr70Ni16Cu6Al8 BMG miniscrew exhibited a high torsion torque even if the miniscrew had a small diameter. Zr70Ni16Cu6Al8 BMG miniscrews with a diameter of 1.1 mm or less had higher stability and lower failure rate than 1.3 mm diameter Ti-6Al-4 V miniscrews. Furthermore, the smaller diameter Zr70Ni16Cu6Al8 BMG miniscrew was shown, for the first time, to have a higher success rate and to form more new bone around the miniscrew. These findings suggested the usefulness of our novel small miniscrew made of Zr70Ni16Cu6Al8 BMG for orthodontic anchorage.https://doi.org/10.1038/s41598-023-30102-3 |
| spellingShingle | Shutaro Sasaki Masahiro Seiryu Hiroto Ida Shunro Miyashita Nobuo Takeshita Daiki Irie Yoshihiko Yokoyama Teruko Takano-Yamamoto Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage Scientific Reports |
| title | Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage |
| title_full | Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage |
| title_fullStr | Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage |
| title_full_unstemmed | Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage |
| title_short | Mechanical properties and biocompatibility of a novel miniscrew made of Zr70Ni16Cu6Al8 bulk metallic glass for orthodontic anchorage |
| title_sort | mechanical properties and biocompatibility of a novel miniscrew made of zr70ni16cu6al8 bulk metallic glass for orthodontic anchorage |
| url | https://doi.org/10.1038/s41598-023-30102-3 |
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