Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells
Summary: Antibody affinity maturation, which is an antigen-based selection process for B cells, occurs in germinal centers (GCs). GCB cells must efficiently recognize, acquire, and present antigens from follicular dendritic cells (FDCs) to receive positive selection signals from T helper cells. Prev...
Main Authors: | Jingjing Chen, Ni Li, Yuye Yin, Nan Zheng, Min Min, Bichun Lin, Le Zhang, Xuehui Long, Yang Zhang, Zhenming Cai, Sulan Zhai, Jun Qin, Xiaoming Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718318874 |
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