Latent cluster analysis of ALS phenotypes identifies prognostically differing groups.

BACKGROUND:Amyotrophic lateral sclerosis (ALS) is a degenerative disease predominantly affecting motor neurons and manifesting as several different phenotypes. Whether these phenotypes correspond to different underlying disease processes is unknown. We used latent cluster analysis to identify groupi...

Full description

Bibliographic Details
Main Authors: Jeban Ganesalingam, Daniel Stahl, Lokesh Wijesekera, Clare Galtrey, Christopher E Shaw, P Nigel Leigh, Ammar Al-Chalabi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2741575?pdf=render