Development and Validation of Chromatographic Methods for Simultaneous Determination of Ibuprofen and Famotidine in Presence of Related Substances in Pharmaceutical Formulations

Development and Validation of Chromatographic Methods for Simultaneous Determination of Ibuprofen and Famotidine in Presence of Related Substances in Pharmaceutical Formulations

Two validated methods for the simultaneous determination of ibuprofen and famotidine in the presence of ibuprofen impurity (4-isobutylacetophenone) and or famotidine degradation products were described. The first method was a simple TLC method where separation was performed on silica gel platesusing...

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Bibliographic Details
Main Authors: Eman S Elzanfaly, Hala E Zaazaa, Aya T Soudi, Maissa Y Salem
Format: Article
Language:English
Published: Slovenian Chemical Society 2014-11-01
Series:Acta Chimica Slovenica
Subjects:
Ibuprofen
Famotidine
Degradation products and impurities
TLC-densitometry
HPLC
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/703

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