Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset
The aim of this study was to establish an early diagnostic system for the identification of the bone metastasis of prostate cancer in whole-body bone scan images by using a deep convolutional neural network (D-CNN). The developed system exhibited satisfactory performance for a small dataset containi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Electronics |
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| Online Access: | https://www.mdpi.com/2079-9292/10/10/1201 |
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| author | Da-Chuan Cheng Chia-Chuan Liu Te-Chun Hsieh Kuo-Yang Yen Chia-Hung Kao |
| author_facet | Da-Chuan Cheng Chia-Chuan Liu Te-Chun Hsieh Kuo-Yang Yen Chia-Hung Kao |
| author_sort | Da-Chuan Cheng |
| collection | DOAJ |
| description | The aim of this study was to establish an early diagnostic system for the identification of the bone metastasis of prostate cancer in whole-body bone scan images by using a deep convolutional neural network (D-CNN). The developed system exhibited satisfactory performance for a small dataset containing 205 cases, 100 of which were of bone metastasis. The sensitivity and precision for bone metastasis detection and classification in the chest were 0.82 ± 0.08 and 0.70 ± 0.11, respectively. The sensitivity and specificity for bone metastasis classification in the pelvis were 0.87 ± 0.12 and 0.81 ± 0.11, respectively. We propose the use of hard example mining for increasing the sensitivity and precision of the chest D-CNN. The developed system has the potential to provide a prediagnostic report for physicians’ final decisions. |
| first_indexed | 2024-03-10T11:18:41Z |
| format | Article |
| id | doaj.art-02436395629044f9a3080cda354df863 |
| institution | Directory Open Access Journal |
| issn | 2079-9292 |
| language | English |
| last_indexed | 2024-03-10T11:18:41Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Electronics |
| spelling | doaj.art-02436395629044f9a3080cda354df8632023-11-21T20:12:39ZengMDPI AGElectronics2079-92922021-05-011010120110.3390/electronics10101201Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small DatasetDa-Chuan Cheng0Chia-Chuan Liu1Te-Chun Hsieh2Kuo-Yang Yen3Chia-Hung Kao4Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 404, TaiwanDepartment of Medical Image, Taipei Medical University-Shuang Ho Hospital, New Taipei 235, TaiwanDepartment of Biomedical Imaging and Radiological Science, China Medical University, Taichung 404, TaiwanDepartment of Biomedical Imaging and Radiological Science, China Medical University, Taichung 404, TaiwanCenter of Augmented Intelligence in Healthcare, China Medical University Hospital, Taichung 404, TaiwanThe aim of this study was to establish an early diagnostic system for the identification of the bone metastasis of prostate cancer in whole-body bone scan images by using a deep convolutional neural network (D-CNN). The developed system exhibited satisfactory performance for a small dataset containing 205 cases, 100 of which were of bone metastasis. The sensitivity and precision for bone metastasis detection and classification in the chest were 0.82 ± 0.08 and 0.70 ± 0.11, respectively. The sensitivity and specificity for bone metastasis classification in the pelvis were 0.87 ± 0.12 and 0.81 ± 0.11, respectively. We propose the use of hard example mining for increasing the sensitivity and precision of the chest D-CNN. The developed system has the potential to provide a prediagnostic report for physicians’ final decisions.https://www.mdpi.com/2079-9292/10/10/1201bone metastasisdeep learninghard example mining |
| spellingShingle | Da-Chuan Cheng Chia-Chuan Liu Te-Chun Hsieh Kuo-Yang Yen Chia-Hung Kao Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset Electronics bone metastasis deep learning hard example mining |
| title | Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset |
| title_full | Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset |
| title_fullStr | Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset |
| title_full_unstemmed | Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset |
| title_short | Bone Metastasis Detection in the Chest and Pelvis from a Whole-Body Bone Scan Using Deep Learning and a Small Dataset |
| title_sort | bone metastasis detection in the chest and pelvis from a whole body bone scan using deep learning and a small dataset |
| topic | bone metastasis deep learning hard example mining |
| url | https://www.mdpi.com/2079-9292/10/10/1201 |
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