Structures of Omicron spike complexes and implications for neutralizing antibody development

Structures of Omicron spike complexes and implications for neutralizing antibody development

Summary: The emergence of the SARS-CoV-2 Omicron variant is dominant in many countries worldwide. The high number of spike mutations is responsible for the broad immune evasion from existing vaccines and antibody drugs. To understand this, we first present the cryo-electron microscopy structure of A...

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Bibliographic Details
Main Authors: Hangtian Guo, Yan Gao, Tinghan Li, Tingting Li, Yuchi Lu, Le Zheng, Yue Liu, Tingting Yang, Feiyang Luo, Shuyi Song, Wei Wang, Xiuna Yang, Henry C. Nguyen, Hongkai Zhang, Ailong Huang, Aishun Jin, Haitao Yang, Zihe Rao, Xiaoyun Ji
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722005344

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