Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms
Farm biosecurity management includes a set of practical measures used to prevent and limit the spread of infections to humans and animals. Infections, predominantly caused by zoonotic agents, often occur due to a lack of safety standards monitoring on farms, but also because of the use of inappropri...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Agriculture |
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| Online Access: | https://www.mdpi.com/2077-0472/12/8/1251 |
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| author | Eugenia Butucel Igori Balta David McCleery Florica Morariu Ioan Pet Cosmin Alin Popescu Lavinia Stef Nicolae Corcionivoschi |
| author_facet | Eugenia Butucel Igori Balta David McCleery Florica Morariu Ioan Pet Cosmin Alin Popescu Lavinia Stef Nicolae Corcionivoschi |
| author_sort | Eugenia Butucel |
| collection | DOAJ |
| description | Farm biosecurity management includes a set of practical measures used to prevent and limit the spread of infections to humans and animals. Infections, predominantly caused by zoonotic agents, often occur due to a lack of safety standards monitoring on farms, but also because of the use of inappropriate antimicrobial products leading to bacterial resistance, tolerance to biocides and the emergence antimicrobial-resistant germs. To date, research was mainly focused on studying the antimicrobial resistance in bacterial biofilms and the mechanisms involved in their occurrence. At molecular level, the limited diffusion of biocides in the biofilm matrix, enzyme-mediated resistance, genetic adaptation, efflux pumps, and levels of metabolic activity inside the biofilm are some of the investigated biological mechanisms which can promote antimicrobial resistance in biofilms were also investigated. Interventions, based on the identification of novel antimicrobial compounds, that would exclude the occurrence of bacterial tolerance, including essential oils (oregano, cloves), organic acids (tannic & oleic acid) and natural plant compounds (e.g. alkaloids, flavonoids, tannins and coumarins) were also extensively studied and reviewed given their effectiveness against pathogen-produced biofilms. The aim of this review was emphasize the importance of biosecurity and farm management practices and to assess their impact on bacterial biofilm formation. Furthermore, we present the recent intervention strategies aimed at reducing and combating the formation of bacterial biofilms in livestock farms. |
| first_indexed | 2024-03-09T12:02:18Z |
| format | Article |
| id | doaj.art-0244a16dd2b84a0c88551472d7254c83 |
| institution | Directory Open Access Journal |
| issn | 2077-0472 |
| language | English |
| last_indexed | 2024-03-09T12:02:18Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Agriculture |
| spelling | doaj.art-0244a16dd2b84a0c88551472d7254c832023-11-30T23:01:28ZengMDPI AGAgriculture2077-04722022-08-01128125110.3390/agriculture12081251Farm Biosecurity Measures and Interventions with an Impact on Bacterial BiofilmsEugenia Butucel0Igori Balta1David McCleery2Florica Morariu3Ioan Pet4Cosmin Alin Popescu5Lavinia Stef6Nicolae Corcionivoschi7Bacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UKBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UKBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UKFaculty of Bioengineering of Animal Resources, University of Life Sciences King Mihai I from Timisoara, 300645 Timisoara, RomaniaFaculty of Bioengineering of Animal Resources, University of Life Sciences King Mihai I from Timisoara, 300645 Timisoara, RomaniaFaculty of Agriculture, University of Life Sciences King Mihai I from Timisoara, 300645 Timisoara, RomaniaFaculty of Bioengineering of Animal Resources, University of Life Sciences King Mihai I from Timisoara, 300645 Timisoara, RomaniaBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UKFarm biosecurity management includes a set of practical measures used to prevent and limit the spread of infections to humans and animals. Infections, predominantly caused by zoonotic agents, often occur due to a lack of safety standards monitoring on farms, but also because of the use of inappropriate antimicrobial products leading to bacterial resistance, tolerance to biocides and the emergence antimicrobial-resistant germs. To date, research was mainly focused on studying the antimicrobial resistance in bacterial biofilms and the mechanisms involved in their occurrence. At molecular level, the limited diffusion of biocides in the biofilm matrix, enzyme-mediated resistance, genetic adaptation, efflux pumps, and levels of metabolic activity inside the biofilm are some of the investigated biological mechanisms which can promote antimicrobial resistance in biofilms were also investigated. Interventions, based on the identification of novel antimicrobial compounds, that would exclude the occurrence of bacterial tolerance, including essential oils (oregano, cloves), organic acids (tannic & oleic acid) and natural plant compounds (e.g. alkaloids, flavonoids, tannins and coumarins) were also extensively studied and reviewed given their effectiveness against pathogen-produced biofilms. The aim of this review was emphasize the importance of biosecurity and farm management practices and to assess their impact on bacterial biofilm formation. Furthermore, we present the recent intervention strategies aimed at reducing and combating the formation of bacterial biofilms in livestock farms.https://www.mdpi.com/2077-0472/12/8/1251farm biosecuritydisinfectioninfection control and preventionanti-biofilm strategiessustainable livestockbiocides |
| spellingShingle | Eugenia Butucel Igori Balta David McCleery Florica Morariu Ioan Pet Cosmin Alin Popescu Lavinia Stef Nicolae Corcionivoschi Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms Agriculture farm biosecurity disinfection infection control and prevention anti-biofilm strategies sustainable livestock biocides |
| title | Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms |
| title_full | Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms |
| title_fullStr | Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms |
| title_full_unstemmed | Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms |
| title_short | Farm Biosecurity Measures and Interventions with an Impact on Bacterial Biofilms |
| title_sort | farm biosecurity measures and interventions with an impact on bacterial biofilms |
| topic | farm biosecurity disinfection infection control and prevention anti-biofilm strategies sustainable livestock biocides |
| url | https://www.mdpi.com/2077-0472/12/8/1251 |
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