Co-Expression Network Analysis and Molecular Docking Demonstrate That Diosgenin Inhibits Gastric Cancer Progression via SLC1A5/mTORC1 Pathway

Co-Expression Network Analysis and Molecular Docking Demonstrate That Diosgenin Inhibits Gastric Cancer Progression via SLC1A5/mTORC1 Pathway

Ning Cui,1 Feng Ding2 1Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, People’s Republic of China; 2Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, People’s Republic of ChinaCorrespondence: Feng Ding, Email dingfengkt@163.comBackground: Tumor...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Cui N, Ding F
Định dạng:	Bài viết
Ngôn ngữ:	English
Được phát hành:	Dove Medical Press 2024-07-01
Loạt:	Drug Design, Development and Therapy
Những chủ đề:	gastric cancer weighted gene co-expression network analysis diosgenin molecular docking diosgenin.
Truy cập trực tuyến:	https://www.dovepress.com/co-expression-network-analysis-and-molecular-docking-demonstrate-that--peer-reviewed-fulltext-article-DDDT

Những quyển sách tương tự

diosgenin effect on rats and mice ovaries
Bằng: israa M. Sulaiman Al-Chalabi
Được phát hành: (2005-10-01)

Identification of diosgenin isolated from genetically engineered tissues cultures of Trigonella foenum-graecum L.
Bằng: M. M. Al-Mahdawe, et al.
Được phát hành: (2014-06-01)

Diosgenin and Its Analogs: Potential Protective Agents Against Atherosclerosis
Bằng: Wang D, et al.
Được phát hành: (2022-07-01)

Unveiling neuroprotective mechanisms of diosgenin and pterostilbene in diabetes-associated Alzheimer’s disease through multi-target molecular docking approach
Bằng: Syeda Jabeen Fatima, et al.
Được phát hành: (2024-10-01)

Fenugreek derived diosgenin as an emerging source for diabetic therapy
Bằng: Yamini Tak, et al.
Được phát hành: (2024-02-01)

Diosgenin And 4-Hydroxyisoleucine From Fenugreek Are Regulators Of Genes Involved In Lipid Metabolism In The Human Colorectal Cancer Cell Line SW480
Bằng: Maryam Mohammad-Sadeghipour, et al.
Được phát hành: (2021-01-01)

Diosgenin-3,6-dione: second polymorph in space group P212121
Bằng: Gabriel Guerrero-Luna, et al.
Được phát hành: (2020-09-01)

Diosgenin and galactomannans, natural products in the pharmaceutical sciences
Bằng: Mohamad Hesam Shahrajabian, et al.
Được phát hành: (2021-06-01)

Insights into diosgenin against inflammatory bowel disease as functional food based on network pharmacology and molecular docking
Bằng: Min Cai, et al.
Được phát hành: (2024-09-01)

DIOSGENIN DETERMINATION OF Costus speciosus WATER EXTRACT USING HPLC METHOD
Bằng: Hari Susanti, et al.
Được phát hành: (2017-04-01)

Diosgenin: Chemistry, extraction, quantification and health benefits
Bằng: Prajya Arya, et al.
Được phát hành: (2023-10-01)

The origin and evolution of the diosgenin biosynthetic pathway in yam
Bằng: Jian Cheng, et al.
Được phát hành: (2021-01-01)

Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model
Bằng: Mingjie Shen, et al.
Được phát hành: (2017-10-01)

Pharmacokinetic Profile and Oral Bioavailability of Diosgenin, Charantin, and Hydroxychalcone From a Polyherbal Formulation
Bằng: Ruchira Salunkhe, et al.
Được phát hành: (2021-04-01)

Diosgenin Loaded Polymeric Nanoparticles with Potential Anticancer Efficacy
Bằng: Nikita Sharma, et al.
Được phát hành: (2020-12-01)

The Effects of Diosgenin on Hypolipidemia and Its Underlying Mechanism: A Review
Bằng: Sun F, et al.
Được phát hành: (2021-09-01)

Two-step Synthesis of Solasodine Pivalate from Diosgenin Pivalate
Bằng: Agnieszka Wojtkielewicz, et al.
Được phát hành: (2019-03-01)

Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice
Bằng: Benneth Ben-Azu, et al.
Được phát hành: (2024-03-01)

HPTLC determination of diosgenin in fenugreek seeds
Bằng: Król-Kogus Barbara, et al.
Được phát hành: (2018-03-01)

Method Development for Quantitative Determination of Diosgenin from the Seeds of Fenugreek, <i>Trigonella foenum-graecum</i> L.
Bằng: A. E. Sukhanov, et al.
Được phát hành: (2020-08-01)

A Novel Diosgenin-Based Liposome Delivery System Combined with Doxorubicin for Liver Cancer Therapy
Bằng: Lixia Chen, et al.
Được phát hành: (2022-08-01)

Validation of the HPLC-UV Method for Quantitative Determination of Steroid Sapogenin Diosgenin from Hay Fenugreek Seeds, Trigonella Foenum-graecum L.
Bằng: A. E. Sukhanov, et al.
Được phát hành: (2020-11-01)

Development of chitosan-folate modified PLGA nanoparticles for targeted delivery of diosgenin as an anticancer agent
Bằng: Fatemeh Teymouri, et al.
Được phát hành: (2024-04-01)

Paris polyphylla Sm. extract enriched with diosgenin as an antidiabetic agent: In vitro and in vivo study
Bằng: Vimi Kshetrimayum, et al.
Được phát hành: (2023-11-01)

Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice
Bằng: Weiyi Shen, et al.
Được phát hành: (2023-06-01)

Nephroprotective role of diosgenin in gentamicin-induced renal toxicity: biochemical, antioxidant, immunological and histopathological approach
Bằng: Prachi Mishra, et al.
Được phát hành: (2021-08-01)

Effect of Diosgenin on the Circulating MicroRNA Profile of Ovariectomized Rats
Bằng: Zhiguo Zhang, et al.
Được phát hành: (2020-03-01)

Identification of genetic variants controlling diosgenin content in Dioscorea zingiberensis tuber by genome-wide association study
Bằng: Shi xian Sun, et al.
Được phát hành: (2024-06-01)

The role of diosgenin in crohn’s disease
Bằng: Sunday Ogundepo, et al.
Được phát hành: (2022-02-01)

Diosgenin alleviates D-galactose-induced oxidative stress in rats’ brain and liver targeting aging and apoptotic marker genes
Bằng: Ali H. El-Far, et al.
Được phát hành: (2024-02-01)

Melatonin confers fenugreek tolerance to salinity stress by stimulating the biosynthesis processes of enzymatic, non-enzymatic antioxidants, and diosgenin content
Bằng: Maryam Mohamadi Esboei, et al.
Được phát hành: (2022-08-01)

Diosgenin Modulates Oxidative Stress and Inflammation in High-Fat Diet-Induced Obesity in Mice
Bằng: Khateeb S, et al.
Được phát hành: (2022-05-01)

Screening and identification of probiotic Lactobacillus for the production of diosgenin from Dioscorea zingiberensis Wright by biotransformation
Bằng: Guowei Shu, et al.
Được phát hành: (2017-09-01)

Diosgenin biosynthesis pathway and its regulation in Dioscorea cirrhosa L.
Bằng: Yan Lin, et al.
Được phát hành: (2024-01-01)

Characterization and Biological Activities of Four Biotransformation Products of Diosgenin from <i>Rhodococcus erythropolis</i>
Bằng: Yanjie Li, et al.
Được phát hành: (2023-03-01)

Design, Synthesis and Biological Evaluation of Diosgenin-Amino Acid Derivatives with Dual Functions of Neuroprotection and Angiogenesis
Bằng: Desheng Cai, et al.
Được phát hành: (2019-11-01)

Effect of Carrier Agents on Quality Parameters of Spray-Dried Encapsulated Diosgenin Powder and the Optimization of Process Parameters
Bằng: Prajya Arya, et al.
Được phát hành: (2023-06-01)

A Method for Improving Microbial Conversion of Diosgenin and Separation and Identification of the Product
Bằng: Fangyuan Mou, et al.
Được phát hành: (2023-01-01)

Diosgenin reverses posttraumatic stress disorder in mice by augmenting neurochemical release and inhibiting HPA axis dysfunction, oxidative stress, and neuroinflammation
Bằng: Benneth Ben-Azu, et al.
Được phát hành: (2024-07-01)

Characterization of spray dried diosgenin from fenugreek using binary blend of carrier agents
Bằng: Prajya Arya, et al.
Được phát hành: (2022-06-01)