Association of Periodontal Disease with Activity of Crohn’s Disease
Introduction: Crohn’s disease (CD) is a chronic inflammatory granulomatous disease that can affect the entire gastrointestinal tract. It is characterized by various extraintestinal manifestations (EIMs), of which oral manifestations (OMs) are often possible. One of the possible OMs is periodontal di...
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| Format: | Article |
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MDPI AG
2023-12-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/12/2154 |
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| author | Miloš Živić Nebojša Zdravković Bojan Stojanović Bojan Milošević Željko Todorović Miljan Adamović Nataša Zdravković |
| author_facet | Miloš Živić Nebojša Zdravković Bojan Stojanović Bojan Milošević Željko Todorović Miljan Adamović Nataša Zdravković |
| author_sort | Miloš Živić |
| collection | DOAJ |
| description | Introduction: Crohn’s disease (CD) is a chronic inflammatory granulomatous disease that can affect the entire gastrointestinal tract. It is characterized by various extraintestinal manifestations (EIMs), of which oral manifestations (OMs) are often possible. One of the possible OMs is periodontal disease (PD), a chronic inflammatory condition of the supporting tissues of the teeth. This study aimed to show the existence of a mutual relationship between the clinical activity of PD and the clinical and endoscopic activity of CD. Materials and methods: One clinical and two endoscopic indexes were used for the assessment of CD activity and clinical attachment loss (CAL), bleeding on probing (BOP), pocket probing depth (PPD), and radiographic bone loss (RBL) in a dental panoramic tomogram to assess PD in CD patients. Results: A total of 38 patients underwent the entire study process, of which 20 patients had CD and 18 patients had CD and PD. Considering all CD activity scores, there were 26 patients with active disease; half of them had PD, and 85.7% of operated patients had active CD. The values of CAL, PPD, BOP, and RBL were higher in active CD patients than those in remission, except for BOP when comparing to the CDAI score, which was higher in those in remission of CD. Conclusion: The results of this study indicate that there is a connection between the activity of CD and worse conditions of the supporting tissues of the gums in the oral cavity, so it is important to keep in mind the necessity of referring patients with CD to a dentist for timely and adequate therapeutic measures. |
| first_indexed | 2024-03-08T20:32:30Z |
| format | Article |
| id | doaj.art-024d49d16e874b7f9004e41f7b4c7642 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-08T20:32:30Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-024d49d16e874b7f9004e41f7b4c76422023-12-22T14:23:58ZengMDPI AGMedicina1010-660X1648-91442023-12-015912215410.3390/medicina59122154Association of Periodontal Disease with Activity of Crohn’s DiseaseMiloš Živić0Nebojša Zdravković1Bojan Stojanović2Bojan Milošević3Željko Todorović4Miljan Adamović5Nataša Zdravković6Department of Dentistry, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, SerbiaDepartment of Medical Statistics and Informatics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, SerbiaDepartment of Surgery, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, SerbiaDepartment of Surgery, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, SerbiaDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, SerbiaPharmacy Institution “Zdravlje Lek”, 11000 Belgrade, SerbiaDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, SerbiaIntroduction: Crohn’s disease (CD) is a chronic inflammatory granulomatous disease that can affect the entire gastrointestinal tract. It is characterized by various extraintestinal manifestations (EIMs), of which oral manifestations (OMs) are often possible. One of the possible OMs is periodontal disease (PD), a chronic inflammatory condition of the supporting tissues of the teeth. This study aimed to show the existence of a mutual relationship between the clinical activity of PD and the clinical and endoscopic activity of CD. Materials and methods: One clinical and two endoscopic indexes were used for the assessment of CD activity and clinical attachment loss (CAL), bleeding on probing (BOP), pocket probing depth (PPD), and radiographic bone loss (RBL) in a dental panoramic tomogram to assess PD in CD patients. Results: A total of 38 patients underwent the entire study process, of which 20 patients had CD and 18 patients had CD and PD. Considering all CD activity scores, there were 26 patients with active disease; half of them had PD, and 85.7% of operated patients had active CD. The values of CAL, PPD, BOP, and RBL were higher in active CD patients than those in remission, except for BOP when comparing to the CDAI score, which was higher in those in remission of CD. Conclusion: The results of this study indicate that there is a connection between the activity of CD and worse conditions of the supporting tissues of the gums in the oral cavity, so it is important to keep in mind the necessity of referring patients with CD to a dentist for timely and adequate therapeutic measures.https://www.mdpi.com/1648-9144/59/12/2154Crohn’s diseaseperiodontal diseaseCrohn’s disease activity indexesperiodontal indexes |
| spellingShingle | Miloš Živić Nebojša Zdravković Bojan Stojanović Bojan Milošević Željko Todorović Miljan Adamović Nataša Zdravković Association of Periodontal Disease with Activity of Crohn’s Disease Medicina Crohn’s disease periodontal disease Crohn’s disease activity indexes periodontal indexes |
| title | Association of Periodontal Disease with Activity of Crohn’s Disease |
| title_full | Association of Periodontal Disease with Activity of Crohn’s Disease |
| title_fullStr | Association of Periodontal Disease with Activity of Crohn’s Disease |
| title_full_unstemmed | Association of Periodontal Disease with Activity of Crohn’s Disease |
| title_short | Association of Periodontal Disease with Activity of Crohn’s Disease |
| title_sort | association of periodontal disease with activity of crohn s disease |
| topic | Crohn’s disease periodontal disease Crohn’s disease activity indexes periodontal indexes |
| url | https://www.mdpi.com/1648-9144/59/12/2154 |
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