Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid

Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid

IntroductionThe relation between rheumatoid arthritis (RA) and periodontitis (PD) has been investigated ever since the discovery of the citrullinating enzyme peptidyl arginine deaminase presents in the oral bacterium Porphyromonas gingivalis. Recently, we demonstrated the presence of RA autoantibodi...

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Main Authors: Menke J. de Smit, Poerwati Soetji Rahajoe, Elisabeth Raveling-Eelsing, Paola Lisotto, Hermie J. M. Harmsen, Nyoman Kertia, Arjan Vissink, Johanna Westra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oral Health
Subjects:
rheumatoid arthritis
anti-citrullinated protein antibodies (ACPA)
periodontitis
mucosal inflammation
microbiome and dysbiosis
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2022.904711/full

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