Controlled Modulation of Serum Protein Binding and Biodistribution of Asymmetric Cyanine Dyes by Variation of the Number of Sulfonate Groups
To assess the suitability of asymmetric cyanine dyes for in vivo fluoro-optical molecular imaging, a comprehensive study on the influence of the number of negatively charged sulfonate groups governing the hydrophilicity of the DY-67x family of asymmetric cyanines was performed. Special attention was...
Main Authors: | Franziska M. Hamann, Robert Brehm, Jutta Pauli, Markus Grabolle, Wilhelm Frank, Werner A. Kaiser, Dagmar Fischer, Ute Resch-Genger, Ingrid Hilger |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2011-07-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2011.00005 |
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