Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma
Purpose: To investigate the changes in choroidal vascular structures after exercise in patients with glaucoma using an image binarisation algorithm with enhanced-depth imaging optical coherence tomography.Methods: Thirty-four eyes of 19 patients with primary open-angle glaucoma and 40 eyes of 20 nor...
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| Format: | Article |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.844795/full |
| _version_ | 1811260707822370816 |
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| author | Dan Cheng Jia Fang Weiqian Gao Minhui Wu Yilin Qiao Kaiming Ruan Hengli Lian Jiner Cen Lin Fu Lijun Shen Li Nie |
| author_facet | Dan Cheng Jia Fang Weiqian Gao Minhui Wu Yilin Qiao Kaiming Ruan Hengli Lian Jiner Cen Lin Fu Lijun Shen Li Nie |
| author_sort | Dan Cheng |
| collection | DOAJ |
| description | Purpose: To investigate the changes in choroidal vascular structures after exercise in patients with glaucoma using an image binarisation algorithm with enhanced-depth imaging optical coherence tomography.Methods: Thirty-four eyes of 19 patients with primary open-angle glaucoma and 40 eyes of 20 normal subjects were included in the glaucoma and control groups, respectively. All subjects were evaluated before, immediately after, and 30 min after 20-min running at moderate speed. The subfoveal choroidal area was segmented into the luminal area (LA) and stromal area (SA), and the choroidal vascularity index (CVI) was measured by calculating the ratio of LA to the total choroidal area (TCA). The mean intraocular pressure (IOP), subfoveal choroidal thickness, CVI, SA, CA, and TCA were compared within and between both groups. The correlation between CVI, IOP, and other vascular indexes was investigated.Results: In the glaucoma group, a significantly lower CVI was found immediately after exercise and recovered 30 min after exercise. Higher TCA and LA levels were demonstrated 30 min after exercise compared to immediately after exercise. In both groups, IOP decreased immediately after exercise but was restored after a 30-min rest. In the glaucoma group, there was a higher correlation between CVI and other choroidal vascular parameters than in the control group. There was no difference in IOP or choroidal parameters between the groups at different time points.Conclusion: In patients with glaucoma, CVI decreased significantly immediately after exercise, indicating that the choroidal layer is affected by exercise and an unhealthy vascular regulatory mechanism. |
| first_indexed | 2024-04-12T18:51:36Z |
| format | Article |
| id | doaj.art-025592270d564762a0389ca781a24c27 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-12T18:51:36Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-025592270d564762a0389ca781a24c272022-12-22T03:20:28ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2022-03-011310.3389/fphys.2022.844795844795Choroidal Vascularity Index Changes After Exercise in Patients With GlaucomaDan Cheng0Jia Fang1Weiqian Gao2Minhui Wu3Yilin Qiao4Kaiming Ruan5Hengli Lian6Jiner Cen7Lin Fu8Lijun Shen9Li Nie10The Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaYongkang First People’s Hospital of Hangzhou Medical College, Yongkang, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, ChinaPurpose: To investigate the changes in choroidal vascular structures after exercise in patients with glaucoma using an image binarisation algorithm with enhanced-depth imaging optical coherence tomography.Methods: Thirty-four eyes of 19 patients with primary open-angle glaucoma and 40 eyes of 20 normal subjects were included in the glaucoma and control groups, respectively. All subjects were evaluated before, immediately after, and 30 min after 20-min running at moderate speed. The subfoveal choroidal area was segmented into the luminal area (LA) and stromal area (SA), and the choroidal vascularity index (CVI) was measured by calculating the ratio of LA to the total choroidal area (TCA). The mean intraocular pressure (IOP), subfoveal choroidal thickness, CVI, SA, CA, and TCA were compared within and between both groups. The correlation between CVI, IOP, and other vascular indexes was investigated.Results: In the glaucoma group, a significantly lower CVI was found immediately after exercise and recovered 30 min after exercise. Higher TCA and LA levels were demonstrated 30 min after exercise compared to immediately after exercise. In both groups, IOP decreased immediately after exercise but was restored after a 30-min rest. In the glaucoma group, there was a higher correlation between CVI and other choroidal vascular parameters than in the control group. There was no difference in IOP or choroidal parameters between the groups at different time points.Conclusion: In patients with glaucoma, CVI decreased significantly immediately after exercise, indicating that the choroidal layer is affected by exercise and an unhealthy vascular regulatory mechanism.https://www.frontiersin.org/articles/10.3389/fphys.2022.844795/fullchoroidal vascularity indexexerciseglaucomaoptical coherence tomographyprimary open-angle glaucoma |
| spellingShingle | Dan Cheng Jia Fang Weiqian Gao Minhui Wu Yilin Qiao Kaiming Ruan Hengli Lian Jiner Cen Lin Fu Lijun Shen Li Nie Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma Frontiers in Physiology choroidal vascularity index exercise glaucoma optical coherence tomography primary open-angle glaucoma |
| title | Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma |
| title_full | Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma |
| title_fullStr | Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma |
| title_full_unstemmed | Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma |
| title_short | Choroidal Vascularity Index Changes After Exercise in Patients With Glaucoma |
| title_sort | choroidal vascularity index changes after exercise in patients with glaucoma |
| topic | choroidal vascularity index exercise glaucoma optical coherence tomography primary open-angle glaucoma |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2022.844795/full |
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